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The Mindfulness of Medicine Development: How Scientists Are Driving the Next Wave of Medical Innovations

For millions of patients around the world, the development of a new treatment or vaccine can be life-changing. But the journey from promising drug candidate to approved product isn’t easy. It's a long and arduous process, with an average timeline lasting more than 10 years.Behind the scenes of these life-changing medical breakthroughs are the scientists whose dedication, expertise, and remarkable problem-solving skills are driving progress forward. Though their training could have prepared them....

Bridging Global Gaps in Hemophilia Care

Pfizer is proud of its commitment to advancing hemophilia care for more than 40 years, dating back to the introduction of recombinant therapies. But while there has been transformative progress as well as advances in the hemophilia treatment landscape during this time, there is still work to be done to ensure more patients receive the best care.Collaboration is an essential component of our efforts to increase access to treatment and bring breakthroughs to people with hemophilia and bleeding....

The Next Era of Decentralized Clinical Trials: The Clinical Trial Anywhere Model

During the early months of 2020, decentralized modalities to conduct clinical trials went mainstream as a solution to a short-term problem: how to continue clinical trials amid pandemic closures. At Pfizer, however, remote trials and the use of digital tools to conduct clinical trials were implemented long before the pandemic. Increased adoption of modalities like telehealth visits became catalysts for how — and where — clinical research could be done.What's more, surveys show that participants....

Harnessing the Power of AI to Detect ATTR-CM

Artificial intelligence (AI) has quietly become a part of our daily lives – through personalized recommendations, virtual assistants, or smart devices, we barely notice it anymore. Yet many of us might not realize the advances AI is making in healthcare. From accelerating drug discovery to improving disease detection, it is transforming the way we understand and manage health.AI has had numerous applications in cardiology in recent years, from analyzing results of cardiac imaging tests to....

In Search of a New Hemophilia Treatment

Despite significant advancements in hemophilia treatments over the past several decades, a fundamental challenge remains for many patients: balancing management of the disorder while maintaining regular day-to-day activities.Historically, treatments could be cumbersome and time-consuming to administer. They typically required intravenous administration up to several times a week to prevent bleeding episodes.1 Even treatments that could be administered at home required infusions multiple times a....

Viral vs Bacterial Infections: Different Pathogens, Different Approaches

When you experience symptoms of an infection such as fever, fatigue, decreased appetite, or pain, knowing whether a virus or bacteria is making you sick may be the key to getting the right treatment and feeling better.1,2Viruses and bacteria are among the most well-known causes of infection.3 Infections occur when viruses or bacteria invade the human host and proliferate.3 But there are some important distinctions between them, and it’s important to determine whether it’s a bacteria or virus....

Pharma Peers Unite to Build DNA-Encoded Libraries

Finding tools and hits for targets in drug discovery can feel like hunting for four leaf clovers in a blizzard. And researcher Sylvie Sakata was close to giving up on one discovery tool, DNA-encoded libraries, when a new consortium started to fall into place. Now this technology is garnering more interest for its potential to discover new molecular compounds, known as “hits,” to exponentially impact the early research efforts that can lead to potential new medicines.Sakata is the Head of....

What You Need to Know About a Promising Vaccine Candidate that May Stem the Growing Risk of Lyme Disease

Lyme disease is the most common vector-borne illness in the United States.1 The U.S. Centers for Disease Control and Prevention (CDC) says that state health departments reported over 63,000 cases in 2022.2 However, the CDC uses other methods to estimate that approximately 476,000 people in the U.S. may be diagnosed and treated for Lyme disease annually.2In other words, the estimated number of Lyme disease cases in the U.S. seems to be much higher than what is being reported to public health....

Caregiver Support: A Guide to Self-Care for Caregivers

A mother helps her daughter through dialysis at night and goes to work without sleep.1 A wife cares for her husband as he spends 110 days recovering from treatment for acute myeloid leukemia in a hospital 250 miles from home.2 A son quits his job to support his mother after she suffers a series of strokes.3Each caregiver’s story is different, but their combined efforts serve as a lifeline to millions of people. Caregivers support children, parents, grandparents, family members, spouses....