Sorry, you need to enable JavaScript to visit this website.
Home Science Areas of Focus Inflammation & Immunology

Inflammation is a critical response to potential danger signals and damage to organs in our body. But with autoimmune diseases such as rheumatoid arthritis, lupus, ulcerative colitis, Crohn’s disease, and many others, our own immune system turns against our organs.

These painful and debilitating conditions take an immense toll on people’s quality of life and many of these diseases are poorly managed by existing treatments that provide only symptomatic relief.

For decades, doctors relied on steroids to suppress immune response. Though an important option, steroids come with many potentially harmful side effects.

Fortunately, science has continued to advance, and today we have the opportunity to transform the management of inflammatory diseases with new classes of therapies that target other key proteins and pathways in the body.

The medicines available today have taken an average of 12 years to develop. With dedication, creativity, and science, we can significantly cut that time.

Our Centers for Therapeutic Innovation collaborates with academic institutions and investigators to push forward great science, using the depth and breadth of the Pfizer enterprise to accelerate concepts into viable therapies with breakthrough potential for patients.

Find Out More About CTI

Revolutionary medicines have the power to enrich and extend life across many disease areas. Explore our latest innovations.

Rare Disease
View All Rare Disease

Explore all of our disease and condition-related resources to learn more about your diagnosis and treatment options. 

Gene Therapy
Duchenne Muscular Dystrophy 
Gaucher Disease
Growth Hormone Deficiency 
Sickle Cell 
Transthyretin Amyloidosis 

Internal Medicine
View All Internal Medicine

We’re developing therapies to treat, slow, or prevent disease progression and improve the quality of life for patients with obesity, type 2 diabetes, and cardiovascular and kidney diseases. 

Inflammation & Immunology
View All Inflammation & Immunology

We look for treatments that provide more than just symptom relief, in order to address the root cause of chronic inflammatory diseases at a molecular level

View All Vaccines

Vaccines are the single most important innovation in the science of health to significantly reduce the threat of diseases that were once widespread and oftentimes fatal. 

Pipeline & Clinical Trials 

View All Oncology

Cancer treatment needs to be transformed across the entire landscape to significantly improve the lives of cancer patients worldwide.

Biology into medicine
Global Impact

Anti Infectives
View All Anti Infectives

Anti-infectives are medicines that work to prevent or treat infections, including antibacterials, antivirals, antifungals, and antiparasitic medications. 

Antimicrobial Resistance 
AMR Prevention 
Antimicrobial Surveillance 
Antimicrobial Stewardship 
Our Commitment as a Global Leader 
Environmental Protection 

The medicines available today have taken an average of 12 years to develop. With dedication, creativity, and science, we can significantly cut that time.

  • 00Phase 1
  • 00Phase 2
  • 00Phase 3
  • 00Registration
  • 00Total

Meet the people behind our medicines. Our experts make discoveries that give the world cutting-edge treatments for conditions that span the range from the common cold to rare diseases.

Media Name: jean_beebe300x170.jpg

Vice President, Clinical Portfolio Leader, I&I Research Unit

Media Name: seng_cheng300x170.jpg

Senior Vice President & Chief Scientific Officer, Rare Disease

Media Name: nanette_cocero300x170.jpg

Global President, Vaccines, Pfizer Biopharmaceuticals Group

Media Name: Olivier_Dirat_300x170px.jpg

Associate Research Fellow and Group Leader, Chemical Development Active Pharmaceutical Ingredients

Media Name: jeff_settleman300x170.jpg

Chief Scientific Officer

Media Name: k_beaverson300x170.jpg

Executive Director, Patient Advocacy Lead

Media Name: Kendra_Bence_300x170px.jpg

Executive Director, Metabolism

Media Name: binks300x170.jpg

Vice President, Clinical Research

Media Name: Julie_Brooks_300x170px.jpg

Postdoctoral Fellow

Media Name: christian_czech300x170.jpg

Senior Director, Biology and Nice Site Lead

Media Name: jeremy_d_gale300x170.jpg

Vice President and Clinical Portfolio Leader

Media Name: grimwood300x170.jpg

Executive Director, Head of Portfolio, Strategy & Operations

Media Name: GRUBER BILL 300x170.jpg

Senior Vice President of Pfizer Vaccine Clinical Research and Development


Chief Medical Officer and Head of Worldwide Medical & Safety

Media Name: K-Jansen_300x170px.jpg

Senior Vice President, Head of Vaccine Research and Development

Luis Jodar bio pic

SVP & Chief Medical Officer, Pfizer Vaccines

Media Name: Nicholas_Kitchin_300x170px.jpg

Senior Director

Media Name: Jennifer_Lafontaine_300x170px.jpg

Senior Director, Oncology Medicinal Chemistry Synthesis and Analytical Group

Media Name: LaRosa_21_300x170.jpg

Vice President, Head of Scientific Research

Media Name: Carolyn_Leverett_300x170px.jpg

Principal Scientist, Oncology Medicinal Chemistry

Media Name: clark_pan_300x170.jpg

Vice President, Gene Therapy and Discovery Biology


Vice President, Rare Neurology and Discovery Biology


Senior Vice President and Chief Scientific Officer, Internal Medicine Research Unit

Media Name: Ravi_Shanker_300x170px.jpg

Senior Research Fellow, Pharmaceutical Sciences

Media Name: Bruce_Thompson_300x170px.jpg

Sr. Principal Scientist, Biotherapeutics Pharmaceutical Sciences

Media Name: Fabien_Vincent_300x170px.jpg

Associate Research Fellow, Hit Discovery and Lead Profiling

Media Name: thomas_a_wynn300x170.jpg

Vice President, Discovery

Media Name: bei_zhang_300x170.jpg

Vice President, Metabolic Research

Learn more about the process of joining a clinical trial and find a trial near you.

Go to Pfizer Clinical Trials Site