PharmSci Senior Project Manager, Portfolio Planning & Digital Enablement
- United States - Connecticut - Groton
ROLE SUMMARY
Why Patients Need You
Pfizer’s purpose is to deliver breakthroughs that change patients’ lives. Pfizer Research and Development is at the heart of fulfilling Pfizer’s purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Critical to this mission is the work done within Pharmaceutical Sciences Small Molecule (PSSM), where we take promising new compounds from the discovery labs and transform them into new best-in-class medicines for patients around the world.
What You Will Achieve
As a Pharmaceutical Sciences (PharmSci) Project Manager you will provide project management, integrated planning, and resource forecasting to PSSM development teams. You will work at the intersection of Business (e.g., creating/managing project budgets, approving inputs and updates to finance) and Science (e.g., interacting with scientists and technical lines across PharmSci) to enable the successful delivery of your projects. You will gain experience working across multiple therapeutic areas (Oncology, Inflammation and Immunology, and Internal Medicine) and support programs across all phases of development (pre-clinical, Phase 1 to 3 clinical, and through commercialization).
In addition, you will leverage your interests and skills in data analytics, digital tools/systems, and AI technologies to embed AI into our work. You will be responsible for leading and shaping our technology solutions for the future.
ROLE RESPONSIBILITIES
Integrated Project Planning
- As a member of the PharmSci Project Team, the Project Manager works with the PharmSci Team Lead (technical project lead) and full cross-functional team to deliver program outcomes within the forecasted timeline and budget.
- Participates in project team meetings and seeks input from team members from PharmSci Science & Technology lines (e.g., Drug Product Design, Analytical R&D, Chemical R&D) to ensure accurate internal (FTE) and external forecasts.
- Partner with Finance to support quarterly forecast updates and annual operating plan / budget build; track purchase orders and accruals to maintain forecast accuracy for assigned programs.
- Maintain accurate and high-quality project plans and proactively identify gaps, risks, and opportunities for improvement to the plan and forecast.
- Propose, lead and implement continuous improvement initiatives
Data Analytics
- Develop scenarios to “base plan” to support project strategy changes (technical, clinical, timeline changes) and prepare detailed analysis of cost / timeline comparisons.
- Prepare portfolio analytics to support ad-hoc senior leadership requests, resource modeling, and Operating Plan processes; summarize assumptions, key drivers, and insights.
- Enable self-service analytics by leveraging approved BI/visualization tools (e.g., Spotfire, Tableau, Power BI, Business Objects) and analytics platforms (e.g., Dataiku) to reduce manual Excel work.
Digital Tools, Systems, and AI Deployment
- Become an expert and PharmSci advocate within the Pfizer “RAPID” enterprise planning and forecasting ecosystem. This includes mastery of Pfizer’s enterprise-wide deployment of Planisware, other supporting systems such as Business Objects, understanding of data / dataflows across ecosystem.
- Transform how PharmSci makes portfolio decisions – powered by analytics, automation, and AI.
- Build and design AI-enabled capabilities (tools, systems, and workflows) to drive productivity, automation, real-time access to data.
- Serve as Business System Owner for custom portfolio systems, including oversight for system maintenance, user interface design, back-end data structures, and continuous improvement.
BASIC QUALIFICATIONS
- B.S. with 10+ years of experience or M.S./MBA degree with 8+ years of experience in scientific or engineering discipline.
- Ability to establish, develop and lead strong working relationships within a matrix organization and team-based environment.
- Demonstrated ability to use data to tell a story.
- High proficiency in Microsoft Excel and PowerPoint, with ability to convert large and complex datasets into charts, graphs, and slides, with explanation / insights clearly articulated.
- Experience with data reporting and visualization tools and platforms, such as Business Objects, Spotfire, Tableau, and/or PowerBI.
- Knowledge and experience building new solutions using contemporary AI platforms and tools (e.g. configuring Snowflake semantic layers for AI/LLM queries).
- Demonstrated ability to work with internal and external digital/technical teams to deliver new solutions.
- Strong attention to detail and accuracy in work products and communications.
- Able to work under tight timelines, multi-task, and prioritize one's work to meet key deadlines.
DESIRED QUALIFICATIONS
- Direct work experience in Pharmaceutical Development / CMC (Chemistry, Manufacturing & Controls) within a large pharmaceutical company, small biotech, or CDMO (contract development and manufacturing organization).
- Experience as business system owner for a custom application and management of system releases working with digital/technical teams.
- Experience working within an enterprise project management tool/system (Planisware or equivalent).
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
Some ad-hoc travel required
Relocation support availableWork Location Assignment: Hybrid

The annual base salary for this position ranges from $116,000.00 to $193,400.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 15.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.




Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers.

Research and Development
Breakthroughs that change patients’ lives
Research confirms what intuition tells us: that purpose-driven companies perform better, are more innovative, attract and retain the best people, and know how to unleash the power of those people. Pfizer’s purpose—Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for building on our legacy as one of the greatest contributors of good to the world.
Each word in our purpose has meaning and reflects the value we strive to bring to patients and society:
“Breakthroughs” - These are the innovations, scientific and commercial, that we seek to deliver every day. All colleagues, regardless of role, level or location, strive for breakthroughs every day.
“Change” - We want to do more than simply improve patients’ medical conditions; we want to dramatically change their lives for the better.
“Patients’ lives” - We consider not only patients, but everyone they touch—including their families, caregivers, and friends—and everything they love to do. It’s an intentionally holistic view.
Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.
Every decision we make and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.
Our Values
To fully realize Pfizer’s purpose, we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.
The “how” is represented by four simple, powerful values—courage, excellence, equity, and joy—that define our company and our culture.
Courage: Breakthroughs start by challenging convention, especially in the face of uncertainty or adversity. This happens when we think big, speak up, and are decisive.
Excellence: We can only change patients’ lives when we perform at our best together. This happens when we focus on what matters, agree who does what, and measure our outcomes.
Equity: We believe that every person deserves to be seen, heard, and cared for. This happens when we are inclusive, act with integrity, and reduce healthcare disparities.
Joy: We give ourselves to our work, but it also gives to us. We find joy when we take pride, recognize one another, and have fun.
Pfizer Research & Development
Pfizer Research & Development serves as the beating heart of Pfizer's trailblazing product pipeline, the essence of our mission to bring life-changing medicines to the world.
With an unwavering commitment to innovation, we use a multidisciplinary approach that blends scientific expertise, cutting-edge technologies, and strategic collaborations, igniting a powerful engine that propels groundbreaking discoveries into life-saving treatments for patients in need.
Through our relentless pursuit of progress, we envision a future where cutting-edge medicines pave the way to healthier, happier lives worldwide.
Benefits at Pfizer
Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues. Our Pay for Performance Philosophy and Practices reward colleagues based on the contributions they make to our business.
Our Competitive Benefits Programs help our colleagues by:
- Promoting Health and Wellness to help colleagues maintain and improve their physical and mental wellbeing. Pfizer offerings include health and disability insurance, preventative health programs, medical screenings, free or reduced-cost vaccinations, discounts on Pfizer products, mental health support, nutrition and fitness counseling and more.
- Strengthening Colleagues’ Financial Security by providing company contributions to retirement plans, life insurance and financial planning education to help colleagues achieve their financial goals.
- Providing Benefits and Time off for the Moments that Matter to ensure Pfizer colleagues have the time away from the office to recharge, recover and return to work as the best version of themselves. Vacation, Holiday time and Sick time are just the beginning, with a 12 week parental leave policy for both parents of a new born, 10 day of caregiver leave for those times when your family needs you whether it’s a child, spouse or parent, bereavement leave, and additional country-specific programs.
- And so much more, depending on your country and site, Pfizer offers childcare facilities or discount programs, on-site health and/or fitness centers, movement and mindfulness solutions, “Log in for your Day” work flexibility and so much more.
For U.S. based jobs, view an overview of Pfizer’s U.S. benefits program (opens in a new window)