Director, HTA, Value & Evidence, Lung Cancer
- United States - New York - New York City
- United States - Any Pfizer Site
- United States - Massachusetts - Cambridge
ROLE SUMMARY
The Director, HTA, Value & Evidence (HV&E), US, Lung Cancer will support the strategic goals of the Oncology Division by driving optimal patient access & appropriate use of medicines within the lung cancer & precision medicine portfolio.
This role directly impacts the ability to achieve business objectives on a US basis by providing strategic guidance and robust evidence development relevant to achieve appropriate use by providers and optimal patient access by demonstrating the value of our medicines. The HV&E Director will be responsible for developing and executing against the US evidence generation strategy, including direct oversight of evidence generation activities and dissemination of technical deliverables, in collaboration with Global HV&E and US Medical.
This position will work closely with Global HVE, GASP, cross-functional US teams, and cross-company alliance partners to foster a culture that promotes innovation, collaboration and thrives on doing better for Pfizer’s patients and for US healthcare providers and systems.
ROLE RESPONSIBILITIES
Lead the development of the evidence generation strategy to support the value of medicines in the lung cancer & precision medicine portfolio in the Oncology Division in close partnership with the cross-functional matrix team.
Lead the coordination of input from US Medical, field-facing colleagues, US Market Access, cross-alliance partners and GASP and USMA team on evidence needs and ensure that the input is appropriately incorporated to develop and integrate the evidence strategy to support market access needs at launch and through lifecycle.
Lead the design and execution of HEOR studies (eg, network meta-analyses, Real World Evidence studies such as non-interventional studies), including studies involving site engagement, chart abstraction, and retrospective data collection, from concept through publication.
Lead the timely development of US value & evidence strategy in coordination with US Medical, Global HV&E, customer-facing deliverables such as AMCP dossiers, systematic literature reviews, economic models, and innovative tools to successfully support reimbursement and access requirements in conjunction with US customer facing teams.
As needed, provide strategic input into clinical trial designs (eg, patient populations, comparators, endpoints) and analysis and interpretation of PRO data to enable successful differentiation negotiations, reimbursement, and appropriate patient access with US payers, and regulatory decision makers.
Partner with internal & cross-alliance stakeholders to ensure appropriate customer facing dissemination of HEOR materials per regulatory guidance and internal SOPs, including development of PVPs, promotional materials and FDAMA 114 compliant materials.
Develop strategic partnerships and research collaborations with key external experts, healthcare policy makers, payers, and various academic and community oncology settings to support asset strategies.
BASIC QUALIFICATIONS
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
- Graduate degree minimum (e.g. MSc, MPH, PhD) required
- 7+ years of experience required with MSc/MPH/MBA degree; 5+ years of experience required with PharmD/PhD in HEOR or relevant related fields (health economics, epidemiology, health services research, or other research-focused public health field)
- Demonstrated in depth understanding of fundamental health services research methods and tools, including health economic modeling, patient-reported outcomes, statistics, and real-world evidence studies including technical and methodological aspects of registries and observational study design, implementation, analysis and interpretation. Capable of independently managing complex non-interventional study projects
- Knowledge and understanding of drug development process and the US healthcare /economic environment.
- Excellent interpersonal skills required: ability to understand and respond to multiple internal and external customers
- Excellent oral and written English communication skills
- Demonstrated ability to assess anticipated value for projects/programs to ensure alignment to business priorities and prioritize accordingly
- An “execution mindset” focused on getting things done quickly and simply
- Strong project management abilities (contracting, budgeting, vendor management) essential. Demonstrated ability to manage multiple projects (multitask) involving complex processes, significant budget, competing deadlines and rapidly shifting priorities
- Ability to influence key members of medical, clinical, cross-alliance and commercial teams constructively and without conflict
- Skilled in functioning within a matrix organization by managing through influence
- Organized and detail oriented with the ability to anticipate needs and to work proactively to prioritize & address/resolve
- Change oriented, comfortable responding to unexpected demands with tight timelines; team player
PREFERRED QUALIFICATIONS
- Demonstrated ability to manage and oversee real-world evidence studies involving clinical sites, medical record review, chart abstraction vendors, data quality oversight, protocol-aligned abstraction processes, and operational execution from study start-up through analysis and reporting is preferred.
- Knowledge and experience in the oncology therapeutic area with lung cancer experience preferred.
- Experience with the US healthcare environment.
- Experience with HTA organizations/submissions such as ICER, CMS-IPAY (IRA) and other HTA groups such as NICE.
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
- Ability to travel domestically and internationally based on business needs
- Ability to work in all US time zones
Other Job Details:
- Last Date to Apply for Job: September 01, 2026
- NOT Eligible for Relocation Package
- Position is hybrid and will require to work 2/3 days a week from site
Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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Market Access
Breakthroughs that change patients’ lives
Research confirms what intuition tells us: that purpose-driven companies perform better, are more innovative, attract and retain the best people, and know how to unleash the power of those people. Pfizer’s purpose—Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for building on our legacy as one of the greatest contributors of good to the world.
Each word in our purpose has meaning and reflects the value we strive to bring to patients and society:
“Breakthroughs” - These are the innovations, scientific and commercial, that we seek to deliver every day. All colleagues, regardless of role, level or location, strive for breakthroughs every day.
“Change” - We want to do more than simply improve patients’ medical conditions; we want to dramatically change their lives for the better.
“Patients’ lives” - We consider not only patients, but everyone they touch—including their families, caregivers, and friends—and everything they love to do. It’s an intentionally holistic view.
Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.
Every decision we make and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.
Our Values
To fully realize Pfizer’s purpose, we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.
The “how” is represented by four simple, powerful values—courage, excellence, equity, and joy—that define our company and our culture.
Courage: Breakthroughs start by challenging convention, especially in the face of uncertainty or adversity. This happens when we think big, speak up, and are decisive.
Excellence: We can only change patients’ lives when we perform at our best together. This happens when we focus on what matters, agree who does what, and measure our outcomes.
Equity: We believe that every person deserves to be seen, heard, and cared for. This happens when we are inclusive, act with integrity, and reduce healthcare disparities.
Joy: We give ourselves to our work, but it also gives to us. We find joy when we take pride, recognize one another, and have fun.
Benefits at Pfizer
Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues. Our Pay for Performance Philosophy and Practices reward colleagues based on the contributions they make to our business.
Our Competitive Benefits Programs help our colleagues by:
- Promoting Health and Wellness to help colleagues maintain and improve their physical and mental wellbeing. Pfizer offerings include health and disability insurance, preventative health programs, medical screenings, free or reduced-cost vaccinations, discounts on Pfizer products, mental health support, nutrition and fitness counseling and more.
- Strengthening Colleagues’ Financial Security by providing company contributions to retirement plans, life insurance and financial planning education to help colleagues achieve their financial goals.
- Providing Benefits and Time off for the Moments that Matter to ensure Pfizer colleagues have the time away from the office to recharge, recover and return to work as the best version of themselves. Vacation, Holiday time and Sick time are just the beginning, with a 12 week parental leave policy for both parents of a new born, 10 day of caregiver leave for those times when your family needs you whether it’s a child, spouse or parent, bereavement leave, and additional country-specific programs.
- And so much more, depending on your country and site, Pfizer offers childcare facilities or discount programs, on-site health and/or fitness centers, movement and mindfulness solutions, “Log in for your Day” work flexibility and so much more.
For U.S. based jobs, view an overview of Pfizer’s U.S. benefits program (opens in a new window)