Senior Associate Scientist Process Chemistry
- United States - Connecticut - Groton
ROLE SUMMARY
We are seeking a synthetic organic chemist to join the Process Chemistry group within Chemical Research and Development (CRD) in Groton, CT. CRD, part of Preclinical and Translational Sciences within Pfizer R&D, is responsible for the development of process technology to produce active pharmaceutical ingredients (APIs). This work includes the synthesis of diverse chemical entities that support both traditional small molecules and emerging therapeutic modalities, including peptides, lipids and other complex synthetic molecules. CRD scientists engage in all facets of development from small scale synthesis in support of discovery programs, to the development of the commercial synthetic routes. CRD scientists partner with manufacturing specialists for API synthesis in kilo-lab and pilot plant facilities, as well as provide support for technology transfer to Pfizer manufacturing sites and third-party facilities.
The successful candidate will enable and develop scalable processes to pharmaceutical drug candidates which are safe, efficient and robust through thoughtful experimentation in a laboratory setting. The ability to work on multi-disciplinary teams involving chemists, analysts, engineers, and technologists is essential.
ROLE RESPONSIBILITIES
The successful candidate will work in the laboratory and assist in the design and execution of synthetic routes to drug candidates including traditional small-molecules, peptides, lipids, and other complex synthetic modalities, within a dynamic, team-oriented environment and assist in the development and completion of experimental studies to provide safe, efficient, robust and scalable processes.
A strong working knowledge of synthetic organic chemistry principles, excellent laboratory skills, an awareness of analytical methods, and a commitment to safety are required. Compliance on safety and regulatory requirements is expected and documented through our internal training program.
The candidate should thrive in the collaborative environment of a multi-disciplinary project team.
A willingness to learn and apply new technology to process development challenges is required.
QUALIFICATIONS
- Master’s degree in Chemistry with laboratory-based research experience required. Pharmaceutical industry experience is preferred but not required.
- Demonstrated high performance in synthetic organic chemistry experimentation with a strong working knowledge of synthetic organic chemistry principles.
- Excellent oral and written communication skills, including the ability to maintain an accurate scientific notebook.
- Familiarization with modern analytical tools and techniques, as well as data interpretation.
- Thorough working knowledge of the published literature in synthetic organic chemistry.
- An ability to communicate results through clear, concise written reports, publications and related documentation.
- Prior experience with peptide and lipid synthesis is highly valued, particularly hands-on experience with route development, scale-up, purification strategies, and cross-functional collaboration in support of pharmaceutical research and development, though it is not required.
PHYSICAL/MENTAL REQUIREMENTS
Laboratory work requires standing.
Working at a computer.
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
Travel is required on occasion in support of external manufacture or to participate in scientific conferences.
Relocation support availableWork Location Assignment: On Premise
The annual base salary for this position ranges from $68,600.00 to $114,300.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Sunshine Act
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EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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Research and Development
Breakthroughs that change patients’ lives
Research confirms what intuition tells us: that purpose-driven companies perform better, are more innovative, attract and retain the best people, and know how to unleash the power of those people. Pfizer’s purpose—Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for building on our legacy as one of the greatest contributors of good to the world.
Each word in our purpose has meaning and reflects the value we strive to bring to patients and society:
“Breakthroughs” - These are the innovations, scientific and commercial, that we seek to deliver every day. All colleagues, regardless of role, level or location, strive for breakthroughs every day.
“Change” - We want to do more than simply improve patients’ medical conditions; we want to dramatically change their lives for the better.
“Patients’ lives” - We consider not only patients, but everyone they touch—including their families, caregivers, and friends—and everything they love to do. It’s an intentionally holistic view.
Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.
Every decision we make and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.
Pfizer Research & Development
Pfizer Research & Development serves as the beating heart of Pfizer's trailblazing product pipeline, the essence of our mission to bring life-changing medicines to the world.
With an unwavering commitment to innovation, we use a multidisciplinary approach that blends scientific expertise, cutting-edge technologies, and strategic collaborations, igniting a powerful engine that propels groundbreaking discoveries into life-saving treatments for patients in need.
Through our relentless pursuit of progress, we envision a future where cutting-edge medicines pave the way to healthier, happier lives worldwide.
Benefits at Pfizer
Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues. Our Pay for Performance Philosophy and Practices reward colleagues based on the contributions they make to our business.
Our Competitive Benefits Programs help our colleagues by:
- Promoting Health and Wellness to help colleagues maintain and improve their physical and mental wellbeing. Pfizer offerings include health and disability insurance, preventative health programs, medical screenings, free or reduced-cost vaccinations, discounts on Pfizer products, mental health support, nutrition and fitness counseling and more.
- Strengthening Colleagues’ Financial Security by providing company contributions to retirement plans, life insurance and financial planning education to help colleagues achieve their financial goals.
- Providing Benefits and Time off for the Moments that Matter to ensure Pfizer colleagues have the time away from the office to recharge, recover and return to work as the best version of themselves. Vacation, Holiday time and Sick time are just the beginning, with a 12 week parental leave policy for both parents of a new born, 10 day of caregiver leave for those times when your family needs you whether it’s a child, spouse or parent, bereavement leave, and additional country-specific programs.
- And so much more, depending on your country and site, Pfizer offers childcare facilities or discount programs, on-site health and/or fitness centers, movement and mindfulness solutions, “Log in for your Day” work flexibility and so much more.
For U.S. based jobs, view an overview of Pfizer’s U.S. benefits program (opens in a new window)