VP, Head of R&D Clinical Creation Center
- United States - Connecticut - Groton
- United States - New York - New York City
- United States - Massachusetts - Cambridge
About the Role
The R&D Clinical Creation Center sits at the intersection of technology and clinical execution, owning the digital, data, and AI capabilities that power the full clinical trial spectrum — from study planning and design through execution, monitoring, and delivery of clean, reportable data. This leader will serve as the single point of accountability in Digital for budget management and for delivery against prioritized R&D impact, defining and driving the strategy for how emerging technologies, including AI, are embedded into how Pfizer plans and runs clinical trials. They will partner closely with CD&O and the broader R&D organization to translate capability into measurable impact.
Key Responsibilities
- Own end-to-end accountability for all digital, data, and AI enablers supporting the clinical trial lifecycle — study planning, design, startup, execution, monitoring, closeout, and reporting.
- Serve as the single point of accountability in Digital for budget management and for delivery against prioritized R&D impact across the R&D Clinical Creation Center portfolio.
- Define and execute a forward-looking technology strategy that incorporates AI and advanced analytics into clinical trial planning, optimization, and delivery.
- Lead the R&D Clinical Creation Center team using product-oriented delivery models and Agile ways of working, shifting from project-based to product-based operating models where appropriate.
- Partner with CD&O, R&D therapeutic areas, biostatistics, and translational medicine leadership to ensure technology investments are grounded in real operational and scientific need.
- Evaluate, select, and integrate emerging platforms and tools (e.g., clinical data capture, eClinical systems) to modernize and simplify the trial technology environment for all consumers: Pfizer colleagues, clinical sites, patients, regulators, et al.
- Build and develop a high-performing, cross-functional team spanning technology, data science, and clinical domain expertise.
- Establish governance, prioritization, and delivery frameworks that balance innovation with regulatory, quality, and compliance requirements.
- Serve as a thought partner to R&D leadership on the future of AI-enabled clinical development.
Required Qualifications
- Bachelor's degree and 15+ years of experience in digital product delivery, with demonstrated success leading technology organizations through modern, product-oriented operating models.
- 5+ years of experience in the clinical domain, including clinical operations, clinical development, or scientific/medical functions.
- Proven track record applying Agile ways of working (Agile WoW) at scale, including experience shifting teams from traditional project delivery to product-centric models.
- Direct experience applying AI/ML to study planning, trial optimization, and/or clinical delivery.
- Strong track record partnering with senior clinical, scientific, and business stakeholders to translate strategy into delivered capability.
- Experience leading through organizational change and ambiguity.
- Demonstrated experience owning and managing a technology budget of significant scale, with accountability for delivery outcomes.
Preferred Qualifications
- Experience with clinical data platforms (e.g., RedCap Cloud, Veeva, or comparable eClinical systems).
- Background in pharmaceutical or biotech R&D technology environments.
- Advanced degree in a relevant scientific, technical, or business discipline.
Last Date to Apply for Job: 10/9/2026
The annual base salary for this position ranges from $274,000.00 to $456,600.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 30.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.


Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers.
Information & Business Tech
Breakthroughs that change patients’ lives
Research confirms what intuition tells us: that purpose-driven companies perform better, are more innovative, attract and retain the best people, and know how to unleash the power of those people. Pfizer’s purpose—Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for building on our legacy as one of the greatest contributors of good to the world.
Each word in our purpose has meaning and reflects the value we strive to bring to patients and society:
“Breakthroughs” - These are the innovations, scientific and commercial, that we seek to deliver every day. All colleagues, regardless of role, level or location, strive for breakthroughs every day.
“Change” - We want to do more than simply improve patients’ medical conditions; we want to dramatically change their lives for the better.
“Patients’ lives” - We consider not only patients, but everyone they touch—including their families, caregivers, and friends—and everything they love to do. It’s an intentionally holistic view.
Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.
Every decision we make and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.
Pfizer Digital
Pfizer Digital takes immense pride in being at the forefront of innovation, harnessing cutting-edge smart technology that profoundly impacts the lives of our patients.
With the transformative potential of digital solutions, we revolutionize how we discover, develop, and deliver medicines, enabling us to achieve breakthroughs faster and more efficiently.
By streamlining and automating transactional processes, we create valuable time and resources, empowering our talented team to focus on meaningful work that truly makes a difference in healthcare and beyond.
Benefits at Pfizer
Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues. Our Pay for Performance Philosophy and Practices reward colleagues based on the contributions they make to our business.
Our Competitive Benefits Programs help our colleagues by:
- Promoting Health and Wellness to help colleagues maintain and improve their physical and mental wellbeing. Pfizer offerings include health and disability insurance, preventative health programs, medical screenings, free or reduced-cost vaccinations, discounts on Pfizer products, mental health support, nutrition and fitness counseling and more.
- Strengthening Colleagues’ Financial Security by providing company contributions to retirement plans, life insurance and financial planning education to help colleagues achieve their financial goals.
- Providing Benefits and Time off for the Moments that Matter to ensure Pfizer colleagues have the time away from the office to recharge, recover and return to work as the best version of themselves. Vacation, Holiday time and Sick time are just the beginning, with a 12 week parental leave policy for both parents of a new born, 10 day of caregiver leave for those times when your family needs you whether it’s a child, spouse or parent, bereavement leave, and additional country-specific programs.
- And so much more, depending on your country and site, Pfizer offers childcare facilities or discount programs, on-site health and/or fitness centers, movement and mindfulness solutions, “Log in for your Day” work flexibility and so much more.
For U.S. based jobs, view an overview of Pfizer’s U.S. benefits program (opens in a new window)