Associate Scientist in Protein Mass Spectrometry
- United States - Connecticut - Groton
ROLE SUMMARY
Pfizer currently has an open position for an Associate Scientist in Protein Mass Spectrometry (MS) within the Structural Analytical and Molecular Sciences (SAMS) department in Groton, CT. We are seeking a highly motivated individual with strong expertise in biochemistry and experimental protein characterization. Experience in native MS, nanoelectrospray applications or MS characterization of large molecules is a strong plus. The successful candidate will demonstrate scientific proficiency from the bench, be a fast learner of new skills, and work effectively in a matrix team environment.
We are an integrated and highly collaborative team of colleagues with technical expertise across molecular biology, protein biochemistry, biophysics, and structural biology. We have a strong track record of enabling hit-to-lead progression for small molecule modulators of diverse protein targets using integrated biophysical and structural approaches. We actively collaborate with Pfizer drug discovery teams across multiple therapeutic areas by providing comprehensive molecular and structural insights into therapeutic targets, lead molecules, and protein-ligand interactions.
ROLE RESPONSIBILITIES
- Learn and deploy native MS and other structural MS methods for deep characterization of protein-ligand interactions
- Handle and manipulate protein samples to enable and execute quantitative and qualitative binding studies.
- Support and maintain open-access MS systems for a suite of users and assist with data collection and processing where needed.
- Be part of multi-disciplinary teams to support discovery projects across diverse disease areas.
- Effective oral and written communication of experimental work and analysis.
- Perform timely notebook entries and review for completed experiments.
QUALIFICATIONS
- BS in chemistry, biochemistry, biophysics, molecular biology or related field with ~1-3 years of relevant laboratory experience.
- Skill and familiarity with handling and manipulating recombinant protein samples
- Ability to multi-task to balance parallel activities.
- Ability to troubleshoot scientific and technical challenges and contribute to their resolution.
- Previous experience with mass spec instrumentation and data analysis is a strong plus.
- Experience using common AI tools, including generative technologies such as ChatGPT or Microsoft Copilot, to support problem solving and enhance productivity.
- Demonstrated curiosity for exploring how these tools can improve outcomes and understanding of responsible AI practices, including risk management and ethical use.
PHYSICAL/MENTAL REQUIREMENTS
Sitting, standing, lifting, bending, and walking. Ability to perform practical laboratory bench work and work on a computer (while standing or sitting). Ability to perform mathematical calculations and interpret data.
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
- Minimal, if any travel related to this position.
- Candidate must comply with laboratory safety practices
Work Location Assignment: On Premise
The annual base salary for this position ranges from $60,200.00 to $100,400.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 7.5% of the base salary. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
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EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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Research and Development
Breakthroughs that change patients’ lives
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Each word in our purpose has meaning and reflects the value we strive to bring to patients and society:
“Breakthroughs” - These are the innovations, scientific and commercial, that we seek to deliver every day. All colleagues, regardless of role, level or location, strive for breakthroughs every day.
“Change” - We want to do more than simply improve patients’ medical conditions; we want to dramatically change their lives for the better.
“Patients’ lives” - We consider not only patients, but everyone they touch—including their families, caregivers, and friends—and everything they love to do. It’s an intentionally holistic view.
Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.
Every decision we make and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.
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With an unwavering commitment to innovation, we use a multidisciplinary approach that blends scientific expertise, cutting-edge technologies, and strategic collaborations, igniting a powerful engine that propels groundbreaking discoveries into life-saving treatments for patients in need.
Through our relentless pursuit of progress, we envision a future where cutting-edge medicines pave the way to healthier, happier lives worldwide.
Benefits at Pfizer
Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues. Our Pay for Performance Philosophy and Practices reward colleagues based on the contributions they make to our business.
Our Competitive Benefits Programs help our colleagues by:
- Promoting Health and Wellness to help colleagues maintain and improve their physical and mental wellbeing. Pfizer offerings include health and disability insurance, preventative health programs, medical screenings, free or reduced-cost vaccinations, discounts on Pfizer products, mental health support, nutrition and fitness counseling and more.
- Strengthening Colleagues’ Financial Security by providing company contributions to retirement plans, life insurance and financial planning education to help colleagues achieve their financial goals.
- Providing Benefits and Time off for the Moments that Matter to ensure Pfizer colleagues have the time away from the office to recharge, recover and return to work as the best version of themselves. Vacation, Holiday time and Sick time are just the beginning, with a 12 week parental leave policy for both parents of a new born, 10 day of caregiver leave for those times when your family needs you whether it’s a child, spouse or parent, bereavement leave, and additional country-specific programs.
- And so much more, depending on your country and site, Pfizer offers childcare facilities or discount programs, on-site health and/or fitness centers, movement and mindfulness solutions, “Log in for your Day” work flexibility and so much more.
For U.S. based jobs, view an overview of Pfizer’s U.S. benefits program (opens in a new window)