Director, US TUKYSA HCP Marketing Lead
- United States - Connecticut - Groton
- United States - Pennsylvania - Collegeville
- United States - New York - New York City
ROLE SUMMARY
Pfizer Commercial Oncology is introducing the world to the next era of cancer care. With a growing portfolio of novel therapies, industry-leading R&D, and a goal of delivering eight breakthroughs by 2030 across major cancer types, we're translating cutting-edge science into market-shaping impact. Here, you'll partner with exceptional colleagues across scientific, medical, and manufacturing teams, backed by advanced digital and AI-enabled infrastructure and the authority to accelerate medicines from discovery to delivery. Guided by our values of courage, excellence, equity, and joy, you'll have the opportunity to stretch your skills and build a career that evolves with you — across teams, roles, and the Pfizer enterprise. Join us to make history — for patients, for their families, for the future.
At Pfizer Oncology, our mission is to "Outdo Cancer" by developing transformative therapies that make a meaningful impact for patients. Pfizer Oncology currently boasts an industry-leading portfolio spanning breast as well as genitourinary (GU) cancers, hematology-oncology, gastrointestinal-oncology, and thoracic cancers. The US Breast Cancer Business is one of the largest businesses within Pfizer Oncology. It is anchored by a multibillion-dollar asset IBRANCE, as well as TUKYSA in metastatic breast cancer, and a robust pipeline of breast cancer innovation.
TUKYSA is entering one of the most consequential windows in the brand's history with the anticipated launch of the HER2CLIMB-05 first-line maintenance (1Lm) indication in human epidermal growth factor receptor 2-positive (HER2+) metastatic breast cancer (mBC, PDUFA Oct 17, 2026). HER2CLIMB-05 marks a new era for the Pfizer Breast Cancer Franchise, with TUKYSA poised as the franchise growth driver. TUKYSA is also indicated for HER2+ metastatic colorectal cancer (mCRC). Over the next years, several pivotal trial readouts are anticipated across both mBC and mCRC for TUKYSA.
The HCP Marketing Lead is a critical strategic and operational leadership role. Operating as an individual contributor in a highly matrixed environment, the Director is the strategic architect of TUKYSA HCP marketing, owning positioning, value proposition, core claims and messaging architecture. The role leads the HCP agency partnership and serves as the primary Marketing partner to Sales for personal promotion, ensuring strategy translates into effective field execution.
The Director, US TUKYSA HCP Marketing Lead will report to the Sr. Director, US TUKYSA Lead and be part of a mission-driven, innovative, and talented team of diverse colleagues, partnering closely with Sales, Insights & Analytics, Medical, Regulatory, Legal and other cross-functional partners.
ROLE RESPONSIBILITIES
- Set and evolve the HCP marketing strategy through launch and beyond, translating emerging customer, competitive and performance dynamics into strategic, executional and investment decisions.
- Define TUKYSA HCP positioning, value proposition, messaging and claims architecture, ensuring compelling competitive differentiation as the market evolves.
- Establish HCP segmentation and targeting strategy, defining priority customers and differentiated engagement approaches in partnership with Insights & Analytics.
- Direct HCP personal promotion from strategy through execution, including core promotional resources, objection handling and MLR review.
- Direct the integrated HCP marketing tactical plan and investment portfolio, making prioritization and resource-allocation decisions across HCP Marketing and establishing success measures with Insights & Analytics.
- Serve as the primary Marketing partner to Sales, translating HCP strategy and messaging into effective field execution and rapidly incorporating field insights.
- Synthesize customer, clinical, competitive and performance insights into strategic action, continually optimizing messaging, execution and investment based on in-market learning.
- Drive HCP marketing execution through others, setting priorities and accountability and providing strategic direction, coaching and development to HCP marketing colleagues and agency partners
Here Is What You Need (Minimum Requirements)
- Bachelor's Degree with 8+ years of experience; OR MBA/MS with 7+ years of experience; OR PhD/PharmD with 5+ years of pharmaceutical/biotech commercial experience, including HCP marketing
- Demonstrated experience developing HCP positioning, messaging, and segmentation strategies.
- Experience leading promotional materials through MLR review
- Ability to independently interpret clinical evidence, primary market research and customer insights and translate them into commercial strategy.
- Demonstrated success leading complex, high-impact initiatives across a matrixed organization.
- Demonstrated ability to influence stakeholders, coach and develop others, and achieve results through the work of other colleagues.
- Strong commercial judgment and demonstrated agency, investment and budget management capabilities.
- Strong written, verbal and executive communication skills.
- Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
Bonus Points If You Have (Preferred Requirements)
- Advanced degree such as MBA, PharmD, PhD or equivalent.
- Oncology commercial experience, particularly breast cancer or solid tumor.
- Launch experience in a highly competitive and evolving market
- Field Sales or other customer-facing experience.
- Experience developing integrated HCP strategies spanning personal and non-personal promotional channels.
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
- Domestic travel of up to 20%.
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
Domestic travel of up to 20%.
Last date to apply: October 27, 2026
The annual base salary for this position ranges from $176,600.00 to $294,300.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.


Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
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EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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Marketing and Market Research
Breakthroughs that change patients’ lives
Research confirms what intuition tells us: that purpose-driven companies perform better, are more innovative, attract and retain the best people, and know how to unleash the power of those people. Pfizer’s purpose—Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for building on our legacy as one of the greatest contributors of good to the world.
Each word in our purpose has meaning and reflects the value we strive to bring to patients and society:
“Breakthroughs” - These are the innovations, scientific and commercial, that we seek to deliver every day. All colleagues, regardless of role, level or location, strive for breakthroughs every day.
“Change” - We want to do more than simply improve patients’ medical conditions; we want to dramatically change their lives for the better.
“Patients’ lives” - We consider not only patients, but everyone they touch—including their families, caregivers, and friends—and everything they love to do. It’s an intentionally holistic view.
Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.
Every decision we make and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.
Benefits at Pfizer
Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues. Our Pay for Performance Philosophy and Practices reward colleagues based on the contributions they make to our business.
Our Competitive Benefits Programs help our colleagues by:
- Promoting Health and Wellness to help colleagues maintain and improve their physical and mental wellbeing. Pfizer offerings include health and disability insurance, preventative health programs, medical screenings, free or reduced-cost vaccinations, discounts on Pfizer products, mental health support, nutrition and fitness counseling and more.
- Strengthening Colleagues’ Financial Security by providing company contributions to retirement plans, life insurance and financial planning education to help colleagues achieve their financial goals.
- Providing Benefits and Time off for the Moments that Matter to ensure Pfizer colleagues have the time away from the office to recharge, recover and return to work as the best version of themselves. Vacation, Holiday time and Sick time are just the beginning, with a 12 week parental leave policy for both parents of a new born, 10 day of caregiver leave for those times when your family needs you whether it’s a child, spouse or parent, bereavement leave, and additional country-specific programs.
- And so much more, depending on your country and site, Pfizer offers childcare facilities or discount programs, on-site health and/or fitness centers, movement and mindfulness solutions, “Log in for your Day” work flexibility and so much more.
For U.S. based jobs, view an overview of Pfizer’s U.S. benefits program (opens in a new window)