Senior Director, Global Obesity Commercial
- United States - New York - New York City
- United States - Massachusetts - Cambridge
ROLE SUMMARY
The Senior Director, Global Obesity Commercial Development serves as a senior strategic leader responsible for shaping Pfizer’s portfolio-level commercial development strategy for the global obesity franchise. This role leads cross-functional strategic integration, drives end-to-end commercial strategy across multiple pipeline assets and indications, and partners with senior leadership on high-impact decisions.
Operating as a senior strategic leader, this role requires a high sense of urgency, the ability to navigate significant ambiguity, and the capability to fluidly shift between asset‑level detail and portfolio‑wide strategic direction. The Senior Director must demonstrate exceptional cross‑functional leadership and communication skills, orchestrating complex integrations across clinical, commercial, and operational stakeholders. As the obesity portfolio progresses toward late‑stage development and early commercialization, this position is critical in ensuring portfolio‑level strategic coherence, enterprise‑aligned decision‑making, and executional readiness across the franchise. A successful candidate will bring deep scientific and business acumen, strong strategic judgment, and a demonstrated ability to influence senior leaders and governance bodies.
ROLE RESPONSIBILITIES
Portfolio-Level Commercial Strategy Leadership
- Lead the shaping of Pfizer’s overarching commercial vision and long-range portfolio strategy.
- Translate market and clinical signals into portfolio-level implications and strategic choices.
- Partner with R&D, Commercial, Finance, and BD to influence investment and lifecycle strategies.
- Oversee forecasting frameworks and scenario planning.
- Identify and shape BD opportunities.
Launch Readiness & Cross-Functional Integration
- Lead global launch readiness strategy across multiple assets and indications.
- Serve as senior integrator across Commercial, R&D, GAV, PGS, BD, and regions.
- Shape capabilities and operating model required to deliver strategy.
- Ensure alignment across global, regional, and market stakeholders.
QUALIFICATIONS
- Bachelor’s degree required; advanced degree strongly preferred.
Experience
- 12+ years in commercial and R&D strategy, commercial development, portfolio strategy, or consulting.
- Strong scientific background
- Leadership shaping end-to-end strategy across multiple assets.
- Strong financial acumen and experience influencing senior leadership.
- Exceptional communication and executive presence.
- Obesity or cardiometabolic experience strongly preferred.
LAST DAY TO APPLY: 11/12/2026
The annual base salary for this position ranges from $214,900.00 to $358,100.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 22.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

This role is posted in multiple locations. If you are applying for the role in an secondary job posting location where pay transparency regulations apply, your Talent Advisor will share the local pay information with you during the first interview.


Relocation assistance may be available based on business needs and/or eligibility.
Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.
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EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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Marketing and Market Research
Breakthroughs that change patients’ lives
Research confirms what intuition tells us: that purpose-driven companies perform better, are more innovative, attract and retain the best people, and know how to unleash the power of those people. Pfizer’s purpose—Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for building on our legacy as one of the greatest contributors of good to the world.
Each word in our purpose has meaning and reflects the value we strive to bring to patients and society:
“Breakthroughs” - These are the innovations, scientific and commercial, that we seek to deliver every day. All colleagues, regardless of role, level or location, strive for breakthroughs every day.
“Change” - We want to do more than simply improve patients’ medical conditions; we want to dramatically change their lives for the better.
“Patients’ lives” - We consider not only patients, but everyone they touch—including their families, caregivers, and friends—and everything they love to do. It’s an intentionally holistic view.
Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.
Every decision we make and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.
Benefits at Pfizer
Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues. Our Pay for Performance Philosophy and Practices reward colleagues based on the contributions they make to our business.
Our Competitive Benefits Programs help our colleagues by:
- Promoting Health and Wellness to help colleagues maintain and improve their physical and mental wellbeing. Pfizer offerings include health and disability insurance, preventative health programs, medical screenings, free or reduced-cost vaccinations, discounts on Pfizer products, mental health support, nutrition and fitness counseling and more.
- Strengthening Colleagues’ Financial Security by providing company contributions to retirement plans, life insurance and financial planning education to help colleagues achieve their financial goals.
- Providing Benefits and Time off for the Moments that Matter to ensure Pfizer colleagues have the time away from the office to recharge, recover and return to work as the best version of themselves. Vacation, Holiday time and Sick time are just the beginning, with a 12 week parental leave policy for both parents of a new born, 10 day of caregiver leave for those times when your family needs you whether it’s a child, spouse or parent, bereavement leave, and additional country-specific programs.
- And so much more, depending on your country and site, Pfizer offers childcare facilities or discount programs, on-site health and/or fitness centers, movement and mindfulness solutions, “Log in for your Day” work flexibility and so much more.
For U.S. based jobs, view an overview of Pfizer’s U.S. benefits program (opens in a new window)