Pipeline Discoveries for Autoimmune Diseases and Chronic Inflammation
Inflammation Immunology Drug Pipeline & Clinical Trials
Pfizer's mission is to deliver medicines that make a real difference in quality of life for patients with autoimmune diseases and chronic inflammation. Scientists in our research and development (R&D) programs are committed to speeding the delivery of new treatments. We pledge to maintain the safety of patients who take part in our trials and to uphold the highest ethical standards in all of our research initiatives.
On this page, you will find more information about our pipeline, which investigational therapies are under development, and in which stages.
If you are a Health Care Professional and interested in further details (including pathways being explored, mechanisms of action of investigational compounds, and an overall summary of investigational compounds organized by therapy area and disease state), please visit our in-depth Pfizer Immunology & Inflammation Research Pipeline site.
PF-06835375 | New project
Lupus (Biologic)
anti-CXCR5
PF-08103402 | New project
Inflammatory Diseases
undisclosed
PF-08065010 | New project
Rheumatoid Arthritis
undisclosed
PF-07832837 | New project
Atopic Dermatitis (Biologic)
undisclosed
Dekavil | New project
Rheumatoid Arthritis (Biologic)
IL-10
PF-07868489 | New project
Pulmonary Arterial Hypertension (Biologic) (ORPHAN – U.S.)
anti-BMP9
PF-06835375 | New project
Immune Thrombocytopenic Purpura (Biologic)
anti-CXCR5
PF-08049820 | New project
Atopic Dermatitis
STAT6 inhibitor
PF-07261271 | New project
Inflammatory Bowel Disease (Biologic)
p40/TL1a bispecific
ompekimig | New project
Atopic Dermatitis (Biologic)
anti-IL-4/ IL-13/ IL-33
tilrekimig (PF-07275315) | New project
Chronic Obstructive Pulmonary Disease
anti-IL-4/ IL-13/ TSLP
LITFULO (ritlecitinib) | New project
Hidradenitis Suppurativa
JAK3/TEC inhibitor
LITFULO (ritlecitinib) | New project
Chronic Spontaneous Urticaria
JAK3/TEC inhibitor
tilrekimig (PF-07275315) | Project advanced
Asthma (Biologic)
anti-IL-4/ IL-13/ TSLP
tilrekimig (PF-07275315) | Project advanced
Atopic Dermatitis (Biologic)
anti-IL-4/ IL-13/ TSLP
osivelotor (PF-07940367) | New project
Sickle Cell Disease (RPD, FAST TRACK, ORPHAN – U.S.)
HbS polymerization inhibitor
dazukibart (PF-06823859) | New project
Dermatomyositis, Polymyositis (Biologic) (ORPHAN - U.S. E.U., FAST TRACK – U.S., PRIME - E.U.)
anti-IFN-B
LITFULO (ritlecitinib) | Project advanced
Moderate Alopecia Areata
JAK3/TEC inhibitor
LITFULO (ritlecitinib) | Project advanced
Vitiligo
JAK3/TEC inhibitor