Vice President, Commercial AI Transformation & Delivery
- United States - New York - New York City
ROLE SUMMARY
As Vice President, Commercial AI Transformation & Delivery, you own the vision, strategy, and delivery of artificial intelligence across Pfizer's U.S. commercial organization. You lead a portfolio of AI and data initiatives spanning sales, marketing, and medical, and you are accountable for turning Pfizer's AI ambition into capabilities that are delivered, adopted, and creating value across the business.
Reporting to the Head of Commercial AI, you lead a multi-disciplinary organization of senior directors, directors, program leaders, and delivery teams, together with a managed network of vendors and delivery partners. While business ownership for individual initiatives sits with their respective business sponsors, you are accountable for end-to-end delivery, technical integrity, talent, and the coherence of the overall portfolio. Your scope spans the U.S. commercial organization and the shared platforms, data, and standards these initiatives build on.
Why This Role Matters
Pfizer's purpose — breakthroughs that change patients' lives — has always depended on the company's willingness to transform how it works, not only what it discovers. Across its history, Pfizer has led large-scale change in how medicines are developed and brought to the patients and clinicians who need them. Becoming the most AI-forward company, and reinventing how we work from end to end, is the next chapter in that story.
This role is central to that ambition for the commercial organization. It brings strategy, technology, and teams together so that AI is applied with rigor and at scale — improving how Pfizer serves patients, customers, and colleagues, and strengthening Pfizer's leadership in the industry. The work is as much about people and ways of working as it is about technology, and this role leads both.
Candidate Profile
This is a senior business and delivery leadership role. It calls for executive leadership, genuine technical credibility, and subject-matter depth in AI. Strong candidates bring three capabilities together rather than excelling in one alone:
AI-native. You have led the development and delivery of production AI — including modern generative and agentic AI — and you reason fluently about how it creates value, where it falls short, and how to deploy it responsibly. You set technical direction and standards through credibility, not by being the hands-on builder.
Enterprise transformation. You have led significant transformation inside large, complex, regulated organizations — reshaping operating models and ways of working, not only delivering technology. You know how to move an organization, not just a roadmap.
Building from the ground up. You have established new capabilities, products, or teams from the ground up and scaled them to real adoption in enterprise settings — comfortable with ambiguity and able to create momentum without waiting for perfect conditions.
ROLE RESPONSIBILITIES
1) Vision, Strategy & Roadmap — Own the vision, strategy, and roadmap for applying AI across the commercial organization. Translate enterprise ambition into a prioritized portfolio of initiatives with clear business value and a credible path to delivery.
2) End-to-End Delivery — Lead delivery of the portfolio from concept through production and adoption. Set priorities, sequence work, resolve dependencies, and make the trade-off calls on scope, investment, and pace.
3) Organization & Talent Leadership — Build and lead a multi-disciplinary organization of senior directors, directors, program leaders, engineers, data scientists, and product leaders. Attract, develop, and retain top talent, and lead other people-leaders.
4) Vendor & Partner Leadership — Build and direct a network of vendors, contractors, and delivery partners. Define the work, set the standard, manage performance and spend, and keep critical capability and intellectual property within Pfizer.
5) Platforms, Standards & Reuse — Ensure initiatives build on shared platforms, data, and engineering standards. Drive reuse and consistency, and prevent duplication and fragmentation across the portfolio.
6) Executive Leadership & Influence — Operate as a trusted partner to senior business and functional leaders. Articulate the vision, influence at the most senior levels, and provide consultative guidance, education, and direction across the organization.
7) Operating Model & Ways of Working — Lead the shift to AI-enabled ways of working. Partner with business leaders and PX on capability building, new roles, and leadership development for an AI-enabled organization.
8) Governance, Risk & Responsible AI — Ensure work is delivered responsibly and in line with Pfizer's legal, regulatory, compliance, privacy, and quality requirements. Embed appropriate governance, controls, and accountability into delivery.
9) Technology & Industry Awareness — Track relevant technology, vendor, and industry developments, and apply them to prioritize and evolve Pfizer's approach. Distinguish durable, valuable capability from hype.
Basic Qualifications
- 15+ years of progressive leadership in technology, data and AI, digital, or product delivery, including senior leadership of large, multi-disciplinary organizations.
- Significant experience in the pharmaceutical, life sciences, or healthcare industry, including an understanding of the commercial environment (sales, marketing, and/or medical) and its regulatory context.
- Proven track record leading complex, enterprise-scale technology or AI programs from strategy through production and adoption, with measurable business impact.
- Experience leading teams that build and operate production AI/ML and data products — with the credibility to set technical direction and standards without needing to be the hands-on engineer.
- Demonstrated success leading large-scale transformation and change in a complex, matrixed enterprise — reshaping operating models and ways of working, not technology alone.
- Track record of establishing new capabilities, products, or businesses from the ground up and scaling them.
- Experience building, leading, and developing senior teams, including other people-leaders, and attracting top technical and product talent.
- Experience owning significant budgets and managing large vendor and partner portfolios.
- Ability to influence and partner with the most senior executives, and to translate complex technology into clear business terms.
- Bachelors Degree Required.
Preferred Qualifications
- Advanced degree in a technical, quantitative, or business discipline, or equivalent experience strongly preferred.
- Deep subject-matter expertise in AI/ML and generative and agentic AI, and how they create value in a commercial setting.
- Direct experience in, or close partnership with, pharmaceutical or healthcare commercial functions.
- Familiarity with enterprise data, platform, and AI governance considerations at scale.
- Recognized leadership presence, internally and externally, on applied AI and transformation.
- Experience operating in a global organization across multiple regions and markets.
Last Day to Apply: June 30, 2026
Location: Must be located onsite 2.5x weekly

The annual base salary for this position ranges from $274,000.00 to $456,600.00. In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 30.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.



Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
To learn more about acceptable and prohibited uses of AI during the recruitment process, please review our candidate AI-use guidelines available on Pfizer Careers.

Information & Business Tech
Breakthroughs that change patients’ lives
Research confirms what intuition tells us: that purpose-driven companies perform better, are more innovative, attract and retain the best people, and know how to unleash the power of those people. Pfizer’s purpose—Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for building on our legacy as one of the greatest contributors of good to the world.
Each word in our purpose has meaning and reflects the value we strive to bring to patients and society:
“Breakthroughs” - These are the innovations, scientific and commercial, that we seek to deliver every day. All colleagues, regardless of role, level or location, strive for breakthroughs every day.
“Change” - We want to do more than simply improve patients’ medical conditions; we want to dramatically change their lives for the better.
“Patients’ lives” - We consider not only patients, but everyone they touch—including their families, caregivers, and friends—and everything they love to do. It’s an intentionally holistic view.
Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.
Every decision we make and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.
Our Values
To fully realize Pfizer’s purpose, we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.
The “how” is represented by four simple, powerful values—courage, excellence, equity, and joy—that define our company and our culture.
Courage: Breakthroughs start by challenging convention, especially in the face of uncertainty or adversity. This happens when we think big, speak up, and are decisive.
Excellence: We can only change patients’ lives when we perform at our best together. This happens when we focus on what matters, agree who does what, and measure our outcomes.
Equity: We believe that every person deserves to be seen, heard, and cared for. This happens when we are inclusive, act with integrity, and reduce healthcare disparities.
Joy: We give ourselves to our work, but it also gives to us. We find joy when we take pride, recognize one another, and have fun.
Benefits at Pfizer
Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues. Our Pay for Performance Philosophy and Practices reward colleagues based on the contributions they make to our business.
Our Competitive Benefits Programs help our colleagues by:
- Promoting Health and Wellness to help colleagues maintain and improve their physical and mental wellbeing. Pfizer offerings include health and disability insurance, preventative health programs, medical screenings, free or reduced-cost vaccinations, discounts on Pfizer products, mental health support, nutrition and fitness counseling and more.
- Strengthening Colleagues’ Financial Security by providing company contributions to retirement plans, life insurance and financial planning education to help colleagues achieve their financial goals.
- Providing Benefits and Time off for the Moments that Matter to ensure Pfizer colleagues have the time away from the office to recharge, recover and return to work as the best version of themselves. Vacation, Holiday time and Sick time are just the beginning, with a 12 week parental leave policy for both parents of a new born, 10 day of caregiver leave for those times when your family needs you whether it’s a child, spouse or parent, bereavement leave, and additional country-specific programs.
- And so much more, depending on your country and site, Pfizer offers childcare facilities or discount programs, on-site health and/or fitness centers, movement and mindfulness solutions, “Log in for your Day” work flexibility and so much more.
For U.S. based jobs, view an overview of Pfizer’s U.S. benefits program (opens in a new window)