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What is AMR?
Antimicrobial Resistance AMR occurs when pathogens change and find ways to resist the effects of antibiotics. The pathogens survive, grow and spread their resistance. This process of adaptation leads to AMR.
Who is at risk of being impacted by AMR?
AMR can affect anyone, of any age, in any country. The World Health Organization (WHO) characterizes AMR, particularly in Gram-negative bacteria, as one of the biggest threats to global public health today.
What is the global impact of AMR?
Globally, AMR causes 700,000 deaths annually. Without action by governments, industry and society, AMR is expected to cause 10,000,000 deaths annually by 2050 —more than currently die from cancer. Failure to act could also result in:
Addressing AMR requires measures to both help prevent and treat resistant infections. This includes both the administration of vaccines to help prevent infections from happening in the first place and using antibiotics to treat infections according to guidelines.
- Review on Antimicrobial Resistance. Tackling a crisis for the health and wealth of nations. December 2014. Available at: https://amr-review.org/sites/default/files/AMR%20Review%20Paper%20-%20Tackling%20a%20crisis%20for%20the%20health%20and%20wealth%20of%20nations_1.pdf Last accessed August 2018.
- Review on Antimicrobial Resistance. Tackling drug-resistant infections globally: final report and recommendations. May 2016. Available at: https://amr-review.org/sites/default/files/160525_Final%20paper_with%20cover.pdf Last accessed August 2018.
- World Health Organization. WHO’s first global report on antibiotic resistance reveals serious, worldwide threat to public health. April 30 2014. Available at: http://www.who.int/mediacentre/news/releases/2014/amr-report/en/ Last accessed August 2018.
- World Health Organization. Antibiotic resistance. February 2018. Available at: http://www.who.int/mediacentre/factsheets/antibiotic-resistance/en/ Last accessed August 2018.
- Vasso S et al. Emerging issues in gram-negative bacterial resistance: an update for the practicing clinician. Mayo Clinic Proc. 2015;90:395-403.
- Centers for Disease Control and Prevention. Making health care safer: protect patients from antibiotic resistance. March 03 2016. Available at: https://www.cdc.gov/vitalsigns/protect-patients/index.html Last accessed August 2018.
- The World Bank. By 2050, drug-resistant infections could cause global economic damage on par with 2008 financial crisis. September 20 2016. Available at: http://www.worldbank.org/en/news/press-release/2016/09/18/by-2050-drug-resistant-infections-could-cause-global-economic-damage-on-par-with-2008-financial-crisis Last accessed August 2018.
- Pfizer 2016 Annual Review. Pfizer Essential Health. Available at: https://www.pfizer.com/files/investors/financial_reports/annual_reports/2016/our-business/global-businesses/pfizer-essential-health/index.html Last accessed August 2018.
- Pfizer. Pfizer policy position on antimicrobial resistance. January 2016. Available at: http://www.pfizer.com/files/about/Position-Antimicrobial-Resistance.pdf Last accessed August 2018.
- Pfizer 2017 Annual Review - Anti-Infectives. Available at: https://www.pfizer.com/files/investors/financial_reports/annual_reports/2017/our-innovation/anti-infectives/index.html Last accessed August 2018.