Global Commercial Oncology CDx Lead
- North America - Any Pfizer Site
- United States - New York - New York City
ROLE SUMMARY
At Pfizer Oncology, we are committed to “Outdo Cancer” by advancing transformative medicines wherever we can make a profound difference in the lives of patients. Today, Pfizer Oncology has an industry-leading pipeline that includes the combined legacy Pfizer and Seagen portfolio across breast, genitourinary, hematology-oncology, thoracic and gastrointestinal therapeutic areas.
The Global Commercial Oncology CDx Lead will drive commercial thought leadership on companion diagnostic global launch strategy for pre-launch oncology assets, including a potential first-in-class integrin-Beta-6 (IB6)-targeting antibody drug conjugate (ADC) sigvotatug vedotin (SV) (should a companion diagnostic be needed). The first commercial launch could potentially be in 2L+ NSCLC in 2027.
The role requires demonstrated experience harmonizing commercial companion diagnostics global launch excellence and Rx launch strategy. Specific experience in global marketing, commercial strategy, market development and alliance management are core to the experience set.
ROLE RESPONSIBILITIES
- Lead the development and execution of global commercial companion diagnostic (CDx) launch strategies that are well-aligned with Rx launch strategies
- Develop and implement global market development plans to drive awareness of testing and adoption of new companion diagnostic solutions, including education, awareness, and stakeholder engagement.
- Lead and manage commercial diagnostic global partnerships to ensure aligned commercial strategies and joint value propositions for CDx and Rx; oversee joint steering committees
- Partner with Oncology R&D Clinical Diagnostics, Clinical Development, Global Medical Affairs, Regulatory, and Global Access & Value teams to ensure seamless incorporation of CDx commercial considerations into clinical development plans
- Partner with US and International commercial teams and Commercial Strategy & Innovation (CSI) to ensure alignment on target product profiles that may incorporate biomarker-selected populations, and global revenue assumptions on biomarker testing
- Deliver Global Guidance for Operating Plan and Long-Range Forecast assumptions for brands that require biomarker testing (i.e., global testing rates, HCP actionability rates) reflective of CDx aspiration as well as risk/benefit to medicine uptake by leveraging real world data
- Drive integration of CDx into specific tumor area treatment ecosystems to optimize patient identification and access to targeted therapies
- Work closely with Global Access & Value team and regional teams to support reimbursement strategies and health technology assessments for CDx.
- Identify and address barriers to CDx uptake, including logistical, operational, and economic challenges.
- Partner with Oncology Customer Analytics & Insights (CAI) to establish standardized KPIs and performance metrics to measure success of CDx initiatives globally.
- Develop detailed, strategic commercialization roadmaps and plans to ensure CDx launch readiness and appropriate planning assessments by partnering closely with the Chief Marketing Office Launch Excellence team.
- Build and maintain relationships with key external stakeholders, including diagnostic companies, healthcare providers, patient advocacy groups, and payers.
- Monitor global market trends, regulatory landscapes, and competitive intelligence to inform strategic decisions and anticipate future needs.
- Conduct all activities and make decisions that are in accordance with Company policies and SOPs, Pfizer Values & global regulatory guidelines, and requests consultation when navigating uncertain situations.
BASIC QUALIFICATIONS
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
- Bachelor’s degree
- 12+ years of commercial experience in the pharmaceutical industry
- Demonstrated experience and expertise leading and executing a successful global pharmaceutical/biotech oncology companion diagnostic launch
- Ability to work independently across senior level stakeholders and demonstrates judgement of what needs to be escalated
- Strong team player with demonstrated ability to engage experts from a wide range of functional areas to improve business performance and find a path forward
- Strong strategic thinking, analytical skills, detail and action oriented, creative, flexible, self-motivated
- Proven track record of translating key insights into meaningful strategies and tactics
- Excellent verbal and written communication skills for a wide range of audiences
- Solid understanding of today’s Global and US pharmaceutical environment, including Regulatory, Legal and Compliance
- Is a role model for the Pfizer Values
PREFERRED QUALIFICATIONS
- Advanced degree
- Oncology precision medicine experience required
- Companion diagnostic launch experience required
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
Ability to travel approximately 20% of the time
ROLE SUMMARY
Breast cancer is the most common cancer affecting women in the US, and IBRANCE, our first-in-class CDK 4/6 inhibitor, along with TUKYSA, our best-in-class HER2 TKI, have been prescribed to over 200,000 patients since launch. In 2025, these two medicines contributed >$3.5B in net revenue to Pfizer Oncology and continue to be market leaders in their respective settings despite intensifying competition. In addition, Pfizer Oncology is preparing to launch novel medicines in breast cancer in the next few years, along with several indication expansions.
The HCP Marketing Director of NPP / Digital position is an opportunity for a results-driven marketing colleague who likes to solve complex business challenges in a dynamic, competitive marketplace. This individual will lead a number of critical and high-visibility commercial initiatives to defend and grow the TUKYSA business through the NPP/digital channels. Given the complexity and interconnected nature of NPP/Digital execution, this position requires involvement and collaboration with the broader US Commercial team, Legal, Medical, Regulatory, Sales, Global, Operations and various other internal stakeholders.
As the HCP NPP/Digital channel Marketing Director, this individual will be responsible for leading the TUKYSA brand strategy in a digital/omnichannel capacity as well as optimizing the brand’s NPP execution and 1:1 targeting across the MBC and mCRC indications. This role requires strong analytical and proactive thinking, clear and concise communication skills, lateral leadership ability, proficient project management and budget management skills, creativity, and a proven track record of success working on a large matrix team. As the HCP NPP / Digital Channel Marketing Director, this individual must be comfortable and working in ambiguity given that digital platforms, activations and requirements are constantly changing.
Additional opportunities and responsibilities will arise and be assigned based on interest, IDPs, and capabilities.
The TUKYSA US Marketing Team is dynamic with lots of opportunity; roles and responsibilities may shift due to business needs and the interests of the individual over time. This role, Director, HCP NPP/Digital, will report to the US TUKYSA Marketing Brand Lead.
ROLE RESPONSIBILITIES
Key Responsibilities include, but are not limited to:
Lead translation of TUKYSA HCP MBC and mCRC brand strategies to NPP/Digital strategies and executions
Drive optimizations within the brand’s HCP MBC and mCRC NPP/Digital ecosystem and ways of working (i.e. develop insight-generating tests and pilots through the NPP/Digital channels; lean into performance/historical data to inform decision making; pioneer tactical, vendor and/or process efficiencies, etc.)
Lead and develop the HCP Branded and Unbranded Websites across all indications; this includes SEO/metadata and SEM/paid search strategy & implementation
Own decision making, vendor management, and scope of the $8-10M HCP TUKYSA Media budget (e.g., design, execution and channel-level spend)
Responsible for the HCP Home Office Email (CRM) channel
Develop video content for HCP audiences to live on our websites or third-party sites
Develop and maintain the HCP MBC Triggered Email & 3P Media journeys
Partner with our Digital Analytics colleagues/vendors to understand performance trends to adjust spend, vendor preference, creative, and flighting of tactics
Collaborate with other Pfizer Digital Marketing Leads or functions to cross-pollinate learnings
Mentor the Senior Product Manager, NPP / Congress
Manage multiple outside agencies and establish optimal ways of working between you and the vendor as well as vendor-to-vendor (i.e. facilitate status calls; manage cross-agency projects, timelines and hand-offs; execute projects from kick-off to MLR to launch while ensuring consistency with product positioning, brand guidelines, company goals, and ethics)
Lead annual Tactical Planning for the HCP NPP/Digital channel (across indications) to include website, media, and email planning
Participate in strategic brand discussions using market research, competitive intelligence/activity, advisory boards and clinical data as rationale for strategy
Identify and mitigate critical issues that impact your individual or cross-channel workstreams and project timelines
Proactively communicate digital strategy/activations to sales colleagues for awareness
BASIC QUALIFICATIONS
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
Bachelor’s Degree or equivalent required and 8+ years pharmaceutical/biotech marketing experience
Oncology experience, with at least 3 years of marketed brand responsibilities
Experience with therapeutics for smaller/ orphan patient populations a plus
Performance in prior positions demonstrates that candidate is well-prepared to advance their Marketing career beyond this role
Demonstrated ability to develop actionable insights from complex clinical data and market research
Knowledge of OPDP regulations and FDA promotional policy, Clinical Development, and Medical Affairs
Experience working in an MLR submission platform
Strong leadership and ability to influence across functional stakeholders, including senior executives, to set direction, align work efforts, and ensure outstanding execution
Strong collaboration skills, working effectively with both internal teams and co-promotion partner
Excellence in additional professional competencies including collaborative and cross functional problem solving and communications, innovative thinking, sense of urgency, and a passion for the science of oncology and for helping patients with cancer.
Experience with the management of external agencies/ vendors as well as project budgets and timelines
Pharmaceutical/biotech sales leadership and/or sales experience preferred
Excellent oral, written and presentation skills
Ability to travel approximately 30% of the time
PREFERRED QUALIFICATIONS
Oncology, specialty, or rare disease NPP/Digital marketing experience
MBA or advanced degree
Experience working within the following platforms: Salesforce Marketing Cloud, Adobe Suite programs, Tableu
Champion innovation, seek learnings from other brands and other industries to innovate and enhance plans
Fosters a culture of collaboration and teamwork
Demonstrated ability to work effectively in a cross-functional team and lead colleagues outside of a direct reporting relationship through influence and persuasion.
Comfort with ambiguity, and complex “white space” environments
Agile mindset; Track record of pushing boundaries and not accepting status quo, finding ways to deliver in the face of accelerated deadlines
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
Domestic travel of up to 30%
Comfort working in a fast-paced environment and making complex decisions quickly
Ability to synthesize and analyze complex data and understand trends and mathematical calculations
Ability to work on computer for extended periods using common applications (Outlook, Excel, PowerPoint)
Ability to travel domestically and internationally as needed for congresses, patient advocacy and customer meetings/interactions
OTHER JOB DETAILS
Last Date to Apply for Job: 12/29/2025
Additional Location Information: New York, NY; Bothell, WA, San Francisco, CA
Relocation might be offered
This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week or more as needed.
Relocation assistance may be available based on business needs and/or eligibility.
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Breakthroughs that change patients’ lives
Research confirms what intuition tells us: that purpose-driven companies perform better, are more innovative, attract and retain the best people, and know how to unleash the power of those people. Pfizer’s purpose—Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for building on our legacy as one of the greatest contributors of good to the world.
Each word in our purpose has meaning and reflects the value we strive to bring to patients and society:
“Breakthroughs” - These are the innovations, scientific and commercial, that we seek to deliver every day. All colleagues, regardless of role, level or location, strive for breakthroughs every day.
“Change” - We want to do more than simply improve patients’ medical conditions; we want to dramatically change their lives for the better.
“Patients’ lives” - We consider not only patients, but everyone they touch—including their families, caregivers, and friends—and everything they love to do. It’s an intentionally holistic view.
Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.
Every decision we make and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.
Our Values
To fully realize Pfizer’s purpose, we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.
The “how” is represented by four simple, powerful values—courage, excellence, equity, and joy—that define our company and our culture.
Courage: Breakthroughs start by challenging convention, especially in the face of uncertainty or adversity. This happens when we think big, speak up, and are decisive.
Excellence: We can only change patients’ lives when we perform at our best together. This happens when we focus on what matters, agree who does what, and measure our outcomes.
Equity: We believe that every person deserves to be seen, heard, and cared for. This happens when we are inclusive, act with integrity, and reduce healthcare disparities.
Joy: We give ourselves to our work, but it also gives to us. We find joy when we take pride, recognize one another, and have fun.
Benefits at Pfizer
Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues. Our Pay for Performance Philosophy and Practices reward colleagues based on the contributions they make to our business.
Our Competitive Benefits Programs help our colleagues by:
- Promoting Health and Wellness to help colleagues maintain and improve their physical and mental wellbeing. Pfizer offerings include health and disability insurance, preventative health programs, medical screenings, free or reduced-cost vaccinations, discounts on Pfizer products, mental health support, nutrition and fitness counseling and more.
- Strengthening Colleagues’ Financial Security by providing company contributions to retirement plans, life insurance and financial planning education to help colleagues achieve their financial goals.
- Providing Benefits and Time off for the Moments that Matter to ensure Pfizer colleagues have the time away from the office to recharge, recover and return to work as the best version of themselves. Vacation, Holiday time and Sick time are just the beginning, with a 12 week parental leave policy for both parents of a new born, 10 day of caregiver leave for those times when your family needs you whether it’s a child, spouse or parent, bereavement leave, and additional country-specific programs.
- And so much more, depending on your country and site, Pfizer offers childcare facilities or discount programs, on-site health and/or fitness centers, movement and mindfulness solutions, “Log in for your Day” work flexibility and so much more.
For U.S. based jobs, view an overview of Pfizer’s U.S. benefits program (opens in a new window)