Sr. Manager, Audience Strategy & Optimization
- United States - New York - New York City

Our Purpose
Our Values
Benefits
ROLE SUMMARY
The Sr. Manager, Audience Strategy & Optimization will support the expansion of digital addressable audiences used across paid, owned and earned Consumer and HCP touchpoints for the Pfizer BioPharma US business. As a critical member of the Audience COE, you will participate in the growth and future roadmap for our audience approach and optimization.
In this role you will partner with Integrated Media Strategy, Analytics, Brand Marketing, Performance Media team, Measurement and other key CMO commercial teams to ensure the audience strategy is aligned with the marketing objectives and KPI’s. The ideal candidate will have a strong background in audience strategy and development, will work well in a matrixed organization, and demonstrate a high level of agility to adapt to changing business needs.
ROLE RESPONSIBILITIES
Support execution of a comprehensive audience strategy across consumer and HCP brands, providing strategic recommendations, partnership, and education to internal stakeholders in implementing key audience functions and tactics.
Assist in establishing, developing and promoting best practices for audience strategy, planning and execution, drive forward consistent standards and processes with creation, execution, measurement and optimization.
Drive expansion of digital audience usage and increase the targeted content that reaches digital audiences across Pfizer, with the goal of improving Marketing ROI
Partner with measurement team to understand performance and optimize to drive brand goals.
Work in partnership with key data providers and partners to develop segments that deliver on brand business needs.
Advisor to the ongoing work with Publicis’ audience data to use their proprietary audience database to optimize and improve audience strategy
Maximize our demand-side platforms (DSPs) capabilities to expand 1:1 audience targeting using individual user-level integrations to inform campaign reach and drive improved performance.
Activate audience strategies with internal brand and product teams to drive usage in Pfizer-owned or managed consumer and HCP experiences
Lead or coordinate initiatives to target HCPs individually to deliver targeted information or branding, via paid, owned and earned media
Represent the voice of the customer/business with respect to product and feature development
Stay informed on emerging audience trends and technologies, including alternative targeting solutions, clean room opportunities, and assist in evaluating and recommending test-and-learn opportunities.
Contribute to and deliver monthly COE updates to key stakeholders and quarterly leadership updates on performance and progress.
Partner across the CMO to build communications plan for how to share out results with the broader marketing organization.
Demonstrate collaborative leadership by fostering effective communication, supporting peers, and contributing to problem-solving efforts that simplify complex challenges.
BASIC QUALIFICATIONS
BA/BS required
6+ years of agency or client-side audience experience (Healthcare expertise preferred but not required)
Proven experience as a leader with a track record of driving growth
Experience working with data & audience partners
Ability to work effectively and collaboratively in a team-based environment
Strong communications skills, and ability to translate concepts for a wide variety of audiences
A deep understanding of audience strategy development, segmentation, targeting, and measurement across media channels.
Understanding of media measurement norms, evolving landscape, and industry standards
A strong analytical mindset with the ability to leverage data to inform strategic decisions and optimize campaign performance
Identify and solve problems effectively, finding creative solutions to challenges
Experience in presenting complex information clearly and concisely to leadership, effectively communicating insights and recommendations
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
Other Job Details:
Last Date to Apply: January 5, 2026
Work Location Assignment: Hybrid
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
Breakthroughs that change patients’ lives
Research confirms what intuition tells us: that purpose-driven companies perform better, are more innovative, attract and retain the best people, and know how to unleash the power of those people. Pfizer’s purpose—Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for building on our legacy as one of the greatest contributors of good to the world.
Each word in our purpose has meaning and reflects the value we strive to bring to patients and society:
“Breakthroughs” - These are the innovations, scientific and commercial, that we seek to deliver every day. All colleagues, regardless of role, level or location, strive for breakthroughs every day.
“Change” - We want to do more than simply improve patients’ medical conditions; we want to dramatically change their lives for the better.
“Patients’ lives” - We consider not only patients, but everyone they touch—including their families, caregivers, and friends—and everything they love to do. It’s an intentionally holistic view.
Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.
Every decision we make and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.
Our Values
To fully realize Pfizer’s purpose, we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.
The “how” is represented by four simple, powerful values—courage, excellence, equity, and joy—that define our company and our culture.
Courage: Breakthroughs start by challenging convention, especially in the face of uncertainty or adversity. This happens when we think big, speak up, and are decisive.
Excellence: We can only change patients’ lives when we perform at our best together. This happens when we focus on what matters, agree who does what, and measure our outcomes.
Equity: We believe that every person deserves to be seen, heard, and cared for. This happens when we are inclusive, act with integrity, and reduce healthcare disparities.
Joy: We give ourselves to our work, but it also gives to us. We find joy when we take pride, recognize one another, and have fun.
Benefits at Pfizer
Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues. Our Pay for Performance Philosophy and Practices reward colleagues based on the contributions they make to our business.
Our Competitive Benefits Programs help our colleagues by:
- Promoting Health and Wellness to help colleagues maintain and improve their physical and mental wellbeing. Pfizer offerings include health and disability insurance, preventative health programs, medical screenings, free or reduced-cost vaccinations, discounts on Pfizer products, mental health support, nutrition and fitness counseling and more.
- Strengthening Colleagues’ Financial Security by providing company contributions to retirement plans, life insurance and financial planning education to help colleagues achieve their financial goals.
- Providing Benefits and Time off for the Moments that Matter to ensure Pfizer colleagues have the time away from the office to recharge, recover and return to work as the best version of themselves. Vacation, Holiday time and Sick time are just the beginning, with a 12 week parental leave policy for both parents of a new born, 10 day of caregiver leave for those times when your family needs you whether it’s a child, spouse or parent, bereavement leave, and additional country-specific programs.
- And so much more, depending on your country and site, Pfizer offers childcare facilities or discount programs, on-site health and/or fitness centers, movement and mindfulness solutions, “Log in for your Day” work flexibility and so much more.
For U.S. based jobs, view an overview of Pfizer’s U.S. benefits program (opens in a new window)
