Director, Enterprise Architect – AI & Data
- Europe - Any Pfizer Site
- United States - Florida - Tampa
- United States - Massachusetts - Cambridge
- United States - Connecticut - Groton
- United States - Pennsylvania - Collegeville
- United States - New York - New York City
ROLE SUMMARY
The Director, AI & Data is responsible for directly overseeing and organizing wide-reaching Pfizer initiatives through digital-wide initiatives, or via horizontal platforms and products. As an individual contributor, your primary impact is through your direct work. You are a widely recognized expert in your technical domain able to articulate clearly to a deep technical level and you are equally comfortable with forming business objectives and producing clear business-facing outcomes.
This role reports to the Senior Director of AI & Data Enterprise Architecture which is responsible for the enterprise-wide architecture of AI & Data.
Key accountabilities:
Support business strategies and priorities across all domains in Pfizer involving AI & Data Enterprise Architecture.
Deliver Enterprise Architecture Outcomes including creation of detailed Solution Sketches, City Plans, and Solution Architecture Diagrams as necessary.
Lead multifaceted, unique, and long-term initiatives with high strategic value, directing colleagues and contractors to produce Enterprise guidance and roadmaps across multiple business lines and global organizations.
Influence and direct a cross- functional team from creation centers, business architects and technical SME’s towards a common technical vision.
Advise Senior leadership on emerging technology landscape externally and internally and enable adoption to minimize total cost of ownership and an optimized application portfolio.
Lead initiatives to bring new technology into Pfizer including the contracting process, co-leading RFIs and RFP responses, and producing a technical fit assessment of each vendor.
ROLE RESPONSIBILITIES
Domain Expertise – Data & AI:
- Establish and enforce enterprise-wide AI standards, governance frameworks, and guardrails to ensure responsible, ethical, and compliant development and deployment of AI solutions across the organization.
- Design and architect a centralized AI platform that supports scalable model development, deployment, monitoring, and lifecycle management for commercial, clinical, and operational use cases.
- Lead the integration of AI/ML solutions into business workflows, ensuring alignment with standardized processes, regulatory requirements, and enterprise architecture principles.
- Develop and maintain architecture roadmaps for data and AI capabilities, aligning technology investments with evolving business models and strategic priorities.
- Drive the adoption of cloud-based data and AI platforms, enabling secure, compliant, and interoperable data pipelines and analytics across business units.
- Establish and oversee data governance frameworks—including master data management, data lineage, and metadata standards—to support high-quality, compliant data for AI and analytics.
- Lead the evaluation and implementation of emerging AI technologies (e.g., generative AI, federated learning, synthetic data) to accelerate digital transformation and maintain competitive advantage.
- Collaborate with cross-functional teams to embed AI-driven decision support into commercial, clinical, and operational workflows, enhancing business agility and innovation.
- Mentor and guide data engineers, data scientists, and business analysts, fostering a culture of innovation, continuous learning, and best practices in data and AI architecture.
Service Delivery:
- Dedicated to meeting the expectations and requirements of internal and external customers; gets first-hand customer information and uses it for improvements in products and services; acts with customers in mind; establishes and maintains effective relationships with customers and gains their trust and respect.
- Understands customers’ operational needs and leads strategic direction in both technical and business context.
- Translates complex business requirements into actionable plans while getting to the root of those requirements and completely understanding the space which you’ll be operating under. You will be responsible for both understanding the business context and providing alternatives to the business plan in addition to translating those to technical blueprints.
- Anticipates internal/external business and GCP compliance issues before they arise, and engage the proper colleagues in the organization to fully document the landscape and provide mitigation strategy and business continuity.
Strategy & Planning:
- Uses innovative business thinking to challenge the status quo and drive identification, quantification, and proposal of business solutions.
- Creates and Leads Enterprise Architecture Initiatives to stay ahead of the technological curve – identifying technologies and solutions before they are implemented.
- Creates actionable plans at the enterprise level to simplify technology systems at every level of the ecosystem.
Architecture
- Understand and develop business drivers and business capabilities (future and current state) and determine corresponding enterprise system designs and change requirements to drive business outcomes.
- Accountable for the formulation of solution implementation approach, building consensus on approach, and providing technical execution oversight of such solutions.
- Knowledgeable about the many different constraints in the healthcare industry. Can educate others on these constraints and provide expert guidance.
- Understands modern cloud architecture best practices and is well-versed in Amazon Web Services-based and Azure architecture.
- Accountable for maintaining technology profiles, influencing, and enforcing technology standards across the enterprise for the best outcome for all of the organization.
Communication:
- Is recognized internally and externally as a thought leader and applies this to influence the strategic direction of a Global Business Unit/Global Operating Unit or Division
- Develops and sustains constructive partnerships between business and technical stakeholders to ensure success of programs and products, over the lifecycle of those initiatives. Is a primary decision maker for technical fit.
- Adept at stakeholder management, with the ability to build and maintain strong relationships across all levels of the organization
- Ensures effective, accurate and timely communication across the portfolio; prepares and delivers regular updates on project status, both in written and presentation format, to sponsors, business leaders and stakeholder groups.
Innovation and Risk Taking
- Creates an environment where innovation is standard taking appropriate risks to advance innovative processes.
- Is knowledgeable about technical and business constraints to produce the best solution.
- Works with other stakeholders to remove roadblocks while ensuring compliance controls are met.
- Financial Management:
- Effectively manages team budget resources in alignment with product / program needs.
- Understands the funding model and is actively engaged in financial planning for projects and products.
- Co-develops business plans for strategic initiatives and for EA organized efforts.
Matrixed Team Effectiveness:
- Is highly skilled in a variety of formal presentation settings; one-on-one, small and large groups, with peers, and senior management; is effective both inside and outside the organization; commands attention and can manage group process during the presentation; can change tactics midstream when something isn't working.
- Utilizes negotiation, facilitation, meeting management and conflict resolution skills to enhance cross-functional team performance.
- Arbitrates disagreements among solution stakeholders and makes business decisions/proposals where needed.
- Understands and communicates team roles/responsibilities and ensures all team members have access to project information necessary to be successful.
- Solicits and evaluates vendor proposals to augment internal expertise in service delivery.
BASIC QUALIFICATIONS
- Bachelor’s Degree / Master’s degree from accredited institution
- 8+ years of experience in AI & Data Technology.
- Deep Technical Knowledge of AI & Data programs, technical designs & patterns in a High Tech and/or Pharma domain.
- Strong interpersonal and Leadership skills where you are not a direct manager
- Strong diplomacy skills; able to navigate a difficult political environment.
- An “execution mindset” focused on getting things done quickly and simply.
PREFERRED QUALIFICATIONS
- 5+ years of experience working with systems that ensure Pharma processes that fully comply with Industry regulations and quality standards (FDA, GxP).
- 5+ years of experience leading the design and architecture of AI & Data solutions to optimize performance across procurement, manufacturing, logistics, and planning.
- Experience with data driven insights to inform decision making and AI-driven technology programs.
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
PHYSICAL/MENTAL REQUIREMENTS
Pfizer Digital is a 7x24x365 global endeavor. This role may require physical or virtual participation on a weekend, holiday, or after normal business hours.
Last Date to Apply for Job: 1/15/2026
The annual base salary for this position ranges from $156,600.00 to $261,000.00.* In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.* The annual base salary for this position in Tampa, FL ranges from $141,000.00 to $235,000.00.Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
Breakthroughs that change patients’ lives
Research confirms what intuition tells us: that purpose-driven companies perform better, are more innovative, attract and retain the best people, and know how to unleash the power of those people. Pfizer’s purpose—Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for building on our legacy as one of the greatest contributors of good to the world.
Each word in our purpose has meaning and reflects the value we strive to bring to patients and society:
“Breakthroughs” - These are the innovations, scientific and commercial, that we seek to deliver every day. All colleagues, regardless of role, level or location, strive for breakthroughs every day.
“Change” - We want to do more than simply improve patients’ medical conditions; we want to dramatically change their lives for the better.
“Patients’ lives” - We consider not only patients, but everyone they touch—including their families, caregivers, and friends—and everything they love to do. It’s an intentionally holistic view.
Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.
Every decision we make and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.
Our Values
To fully realize Pfizer’s purpose, we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.
The “how” is represented by four simple, powerful values—courage, excellence, equity, and joy—that define our company and our culture.
Courage: Breakthroughs start by challenging convention, especially in the face of uncertainty or adversity. This happens when we think big, speak up, and are decisive.
Excellence: We can only change patients’ lives when we perform at our best together. This happens when we focus on what matters, agree who does what, and measure our outcomes.
Equity: We believe that every person deserves to be seen, heard, and cared for. This happens when we are inclusive, act with integrity, and reduce healthcare disparities.
Joy: We give ourselves to our work, but it also gives to us. We find joy when we take pride, recognize one another, and have fun.
Pfizer Digital
Pfizer Digital takes immense pride in being at the forefront of innovation, harnessing cutting-edge smart technology that profoundly impacts the lives of our patients.
With the transformative potential of digital solutions, we revolutionize how we discover, develop, and deliver medicines, enabling us to achieve breakthroughs faster and more efficiently.
By streamlining and automating transactional processes, we create valuable time and resources, empowering our talented team to focus on meaningful work that truly makes a difference in healthcare and beyond.
Benefits at Pfizer
Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues. Our Pay for Performance Philosophy and Practices reward colleagues based on the contributions they make to our business.
Our Competitive Benefits Programs help our colleagues by:
- Promoting Health and Wellness to help colleagues maintain and improve their physical and mental wellbeing. Pfizer offerings include health and disability insurance, preventative health programs, medical screenings, free or reduced-cost vaccinations, discounts on Pfizer products, mental health support, nutrition and fitness counseling and more.
- Strengthening Colleagues’ Financial Security by providing company contributions to retirement plans, life insurance and financial planning education to help colleagues achieve their financial goals.
- Providing Benefits and Time off for the Moments that Matter to ensure Pfizer colleagues have the time away from the office to recharge, recover and return to work as the best version of themselves. Vacation, Holiday time and Sick time are just the beginning, with a 12 week parental leave policy for both parents of a new born, 10 day of caregiver leave for those times when your family needs you whether it’s a child, spouse or parent, bereavement leave, and additional country-specific programs.
- And so much more, depending on your country and site, Pfizer offers childcare facilities or discount programs, on-site health and/or fitness centers, movement and mindfulness solutions, “Log in for your Day” work flexibility and so much more.
For U.S. based jobs, view an overview of Pfizer’s U.S. benefits program (opens in a new window)