Senior Associate Scientist
- United States - New York - Pearl River

Use Your Power for Purpose
At Pfizer, our purpose is to deliver breakthroughs that change patients’ lives. As a Senior Associate Scientist Biology, you will be at the forefront of our mission, contributing to the development of innovative therapies and vaccines that have the potential to transform patient care.
We are seeking a highly motivated Senior Associate Scientist with advanced expertise in next generation sequencing (NGS) to join the NGS/Data Science team within Vaccines Research in Pearl River. This is a primarily laboratory-based role supporting ongoing research and development initiatives.
The successful candidate will collaborate closely with multidisciplinary partners to advance and apply NGS technologies across vaccine programs. Key responsibilities include executing assays with precision, managing deliverables, maintaining laboratory readiness, participating in project meetings, and organizing action items. Additionally, this role requires meticulous documentation practices, attention to detail, strong analytical and problem-solving skills, and sound critical thinking.
Along with adhering to established laboratory procedures, the ideal candidate should demonstrate scientific curiosity and enthusiasm for developmental and exploratory work. A solid foundation in DNA/RNA biology, qPCR assay development, genetics, molecular biology, and mechanisms of genomic mutation and variation is required.
What You Will Achieve
In this role, you will:
Execute NGS protocols to support vaccine program initiatives.
Conduct laboratory-based activities, including sample organization and preparation, DNA/RNA purification, library construction, qPCR, tissue processing, and related tasks.
Operate, maintain, optimize, and manage laboratory automation systems; develop and improve automated workflows.
Develop innovative sequencing protocols for pathogen and/or human genome characterization using Ion Torrent and Illumina platforms.
Demonstrate advanced problem-solving abilities, including troubleshooting and resolution of technical issues with high-level of independence.
Manage project timelines effectively and work efficiently on assigned tasks.
Maintain current knowledge of scientific literature and emerging technologies; attend relevant scientific meetings to integrate new technologies and principles as appropriate.
Perform molecular biology research, data analysis, and other tasks aligned with program needs.
Complete all required safety training in accordance with departmental standards. Where applicable, ensure compliance with GxP and other relevant regulatory requirements.
Here Is What You Need (Minimum Requirements)
Bachelor’s degree in Molecular Biology, Virology, Immunology, or a related scientific discipline with 4–5 years of relevant laboratory experience, or a Master’s degree with 2–3 years of relevant hands-on laboratory experience.
Minimum of two years’ experience working with NGS technologies.
Proficiency with a wide range of molecular biology and analytical techniques, including nucleic acid extraction, fluorescence-based quantification, and real-time PCR.
Exceptional task planning, problem-solving abilities, and ability to manage multiple priorities effectively.
Effective verbal and written communication skills
Bonus Points If You Have (Preferred Requirements)
Experience and programming capabilities with laboratory automation systems, e.g. Biomek, Hamilton, or similar liquid handling systems
Experience working in a regulated laboratory environment
Familiarity with LIMS system or other digital laboratory information systems
Demonstrated abilities to rapidly learn new technical skills and concepts
Experience with single-cell RNA-seq and/or immune profiling NGS assays
PHYSICAL/MENTAL REQUIREMENTS
This job will require lifting/moving objects in a laboratory setting less than 30 Ibs.
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
BSL2 working requirements
Willing to work for extended hours when meeting urgent timelines (very rare)
Relocation support available
Work Location Assignment: On Premise
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
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EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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