Senior Manager, NP&LCM Portfolio Lead
- Europe - Remote
- United States - Any Pfizer Site
- United States - Remote
- United States - Florida - Tampa
- Ireland - Kildare - Newbridge
- United Kingdom - Sandwich
- United States - Connecticut - Groton
- Ireland - Cork - Ringaskiddy
- Germany - Freiburg
Use Your Power for Purpose
At Pfizer, our mission is to cultivate a best-in-class culture of continuous improvement and project management, empowering colleagues and streamlining processes. Whether managing projects or driving strategic initiatives, your role in this team is crucial in simplifying and accelerating our work. This enables us to deliver breakthroughs that transform patients' lives. Your contributions make our operations more efficient and effective, driving us towards our goal of making a significant impact on healthcare.
What You Will Achieve
The New Product (NP) & Lifecycle Managment (LCM) Portfolio Lead comprises two primary roles: a Co-Development Lead (CDL) & a Technology Team Lead (TTL). The CDL is responsible for serving as the primary PGS representative in developing and leading late-stage small-molecule product development, ensuring PGS considerations are reflected in Co-Development project plans across all technologies (API/Analytical/Drug Product/Packaging) in partnership with Pharm Sci & PGS. The CDL role leads a PGS cross site and cross functional product focused team(s) and is responsible for PGS input into CMC strategy development and execution as well as PGS at risk spend elements of the overall CMC budget of late-stage clinical product development (Co-Development). For each product assigned, the candidate will drive PGS input to product strategy and provide this input across the co-development process. Including development, manufacturing and regulatory submission content to deliver the Quality Target Product Profile (QTPP), Validation and Launch strategies, knowledge management (including delivery of Process Understanding Plans (PUPs)), project timelines, key project milestones, and lessons learned. The TTL is responsible for serving as the primary technical PGS representative in managing in-line, or marketed, products, ensuring PGS technical considerations are reflected in Technology Lifecycle plans across all technologies (API/Analytical/Drug Product/Packaging) in partnership with other PGS functions. The TTL role leads a PGS cross-site and cross-functional product-focused team and is responsible for facilitating evaluation & implementation of technical projects related to product supply (including product quality/compliance) and/or cost-savings and understanding & communicating product risks & project milestones.
The candidate will build relationships with business line partners (Business Units, Pfizer Research & Development (PRD), Pfizer Global Supply (PGS) functions and manufacturing sites, and small molecule Pharm Sciences (PSSM)) to advocate for the strategies, plans and timelines of Co-Development Team(s) & Technology Team(s).
Develop and lead complex projects, creating and managing plans to achieve objectives.
Manage and oversee the operational aspects of ongoing improvement projects, acting as a liaison between project teams and line management.
Support programs by managing project status reviews, budgets, schedules, and preparing necessary reports.
Develop mechanisms for monitoring project progress, intervening, and problem-solving with project managers, line managers, and clients.
Facilitate the development, implementation, and management of business strategies, coordinating project plans with cross-functional teams to deliver on time and within budget.
Execute communication plans to ensure effective and timely communication among the core team, functional management, senior management, and external partners.
Promote a continuous improvement culture, streamline processes for maximum efficiency, and provide project information to support portfolio-level decision-making and prioritization.
Represent PGS on the Co-Development Team (CDT) & PGS technical on the Product Team (PT)..
As the PGS lead on the cross-functional matrix CDTs, work closely with PSSM, manufacturing sites, GMTs, and Business Unit, to evaluate technology and processes to transfer, validate, and submit CMC regulatory modules to health authorities, gain marketing approval, and launch new small-molecule products and in some cases support post approval major product enhancements of marketed products (e.g. new devices / formulations, line extensions).
Provide PGS input into CMC strategy development, execution, and CMC budget.
Serve as PGS point of contact to enable delivery of clinical supply plan for pivotal / Phase 3 studies.
Provide PGS input into communications and alignment with key stakeholders, including in escalation of major changes and issues, project risks and opportunities.
Provide PGS input into decision making in environment of competing priorities and varying levels of ambiguity.
Partner with Pharm Sci Team Leader (PSTL) in Co-Development & Product Portfolio Lead (PPL) in Marketed Product Support to create highly empowered and cohesive team(s) that can rally behind a compelling vision.
Represent PGS on the CDT to help develop Co-Development plans including ICH and validation strategy for CDTs.
Represent PGS technical on the PT to help develop Technology Lifecycle plans, including key projects related to supply continuity & cost-savings.
Develop and track at-risk spend for pre-launch inventory as part of the op planning process.
Represent PGS on Joint Alliance Teams as needed (i.e. Joint Development Team, Joint Supply Chain Team, Joint Steering Team). Lead Alliance Joint Manufacturing Committee as needed
Lead key strategic projects / initiatives with ambiguous scope to enable Pfizer Purpose Blueprint and deliver value to organization, as needed
Here Is What You Need (Minimum Requirements)
BA/BS with 6+ years of experience or MBA/MS with 5+ years of experience
Demonstrated ability to effectively lead matrix teams; ensuring successful completion of major programs / projects as part of a team and/or project leadership role. Experience leading highly accelerated or high complexity projects.
Demonstrated ability to interact effectively with colleagues at all levels of the organization, including senior internal and/or external personnel on matters often requiring coordination between organizations; able to build effective relationships and influence stakeholders at all levels of the organization.
Able to develop solutions to complex problems using ingenuity, innovation, creativity, and leadership skills.
Extensive technical and industry-specific expertise in drug development and/or manufacturing. Specific experience in small-molecule products area strongly preferred.
Understanding of process of developing small-molecule drugs and CMC requirements.
Flexible and adaptable to changing priorities and timelines (acceleration/deceleration), meeting deadlines, and working well under pressure.
Comfortable working independently on high complexity assignments. Adept at developing processes necessary to accomplish goals. Simplifies complex processes. Skilled at organizing people and activities. Demonstrated ability to identify opportunities for synergy and integration. See and understand broader trends (organizational, run the business, improve the business) and come up with proactive solutions,
Effective written and verbal communication skills. Clearly and concisely summarize complex issues, key outcomes, and importance to the audience, including senior leaders; able to work with different cultures.
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
Bonus Points If You Have (Preferred Requirements)
Experience with API and DP development & scale-up of small-molecule products.
Experience with technical transfer of small-molecule products.
Experience with co-development process for new small-molecule products.
Experience with Pfizer budget processes, including managing project budgets (expense spending and FTEs).
Understanding of Business Development processes.
Experience using common AI tools, including generative technologies such as ChatGPT or Microsoft Copilot, to support problem solving and enhance productivity. Demonstrated curiosity for exploring how these tools can improve outcomes and understanding of responsible AI practices, including risk management and ethical use
PHYSICAL/MENTAL REQUIREMENTS
Significant time on laptop & telecons
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
~20% travel
Last date to apply: March 31, 2026

The annual base salary for this position ranges from $124,400.00 to $207,400.00.* In addition, this position is eligible for participation in Pfizer’s Global Performance Plan with a bonus target of 17.5% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life’s moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site – U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

* The annual base salary for this position in Tampa, FL ranges from $111,900.00 to $186,500.00.

Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
Breakthroughs that change patients’ lives
Research confirms what intuition tells us: that purpose-driven companies perform better, are more innovative, attract and retain the best people, and know how to unleash the power of those people. Pfizer’s purpose—Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for building on our legacy as one of the greatest contributors of good to the world.
Each word in our purpose has meaning and reflects the value we strive to bring to patients and society:
“Breakthroughs” - These are the innovations, scientific and commercial, that we seek to deliver every day. All colleagues, regardless of role, level or location, strive for breakthroughs every day.
“Change” - We want to do more than simply improve patients’ medical conditions; we want to dramatically change their lives for the better.
“Patients’ lives” - We consider not only patients, but everyone they touch—including their families, caregivers, and friends—and everything they love to do. It’s an intentionally holistic view.
Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.
Every decision we make and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.
Our Values
To fully realize Pfizer’s purpose, we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.
The “how” is represented by four simple, powerful values—courage, excellence, equity, and joy—that define our company and our culture.
Courage: Breakthroughs start by challenging convention, especially in the face of uncertainty or adversity. This happens when we think big, speak up, and are decisive.
Excellence: We can only change patients’ lives when we perform at our best together. This happens when we focus on what matters, agree who does what, and measure our outcomes.
Equity: We believe that every person deserves to be seen, heard, and cared for. This happens when we are inclusive, act with integrity, and reduce healthcare disparities.
Joy: We give ourselves to our work, but it also gives to us. We find joy when we take pride, recognize one another, and have fun.
Pfizer Global Supply
Pfizer Global Supply proudly shoulders the responsibility of manufacturing and distributing our wide-ranging pharmaceutical products.
With an unwavering commitment to ensuring the availability and accessibility of these life-saving medications, we play a pivotal role in reaching patients, healthcare professionals, and markets across the globe.
Our network of state-of-the-art manufacturing facilities, strategically located distribution centers, and streamlined logistics systems enables us to deliver Pfizer's medicines with utmost efficiency and reliability, making a tangible difference in patients' lives worldwide.
Benefits at Pfizer
Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues. Our Pay for Performance Philosophy and Practices reward colleagues based on the contributions they make to our business.
Our Competitive Benefits Programs help our colleagues by:
- Promoting Health and Wellness to help colleagues maintain and improve their physical and mental wellbeing. Pfizer offerings include health and disability insurance, preventative health programs, medical screenings, free or reduced-cost vaccinations, discounts on Pfizer products, mental health support, nutrition and fitness counseling and more.
- Strengthening Colleagues’ Financial Security by providing company contributions to retirement plans, life insurance and financial planning education to help colleagues achieve their financial goals.
- Providing Benefits and Time off for the Moments that Matter to ensure Pfizer colleagues have the time away from the office to recharge, recover and return to work as the best version of themselves. Vacation, Holiday time and Sick time are just the beginning, with a 12 week parental leave policy for both parents of a new born, 10 day of caregiver leave for those times when your family needs you whether it’s a child, spouse or parent, bereavement leave, and additional country-specific programs.
- And so much more, depending on your country and site, Pfizer offers childcare facilities or discount programs, on-site health and/or fitness centers, movement and mindfulness solutions, “Log in for your Day” work flexibility and so much more.
For U.S. based jobs, view an overview of Pfizer’s U.S. benefits program (opens in a new window)