Director, Integrated Insights and Strategy (IIS), Obesity Lifecycle Lead
- United States - Pennsylvania - Collegeville
- United States - New York - New York City
Role Summary
Pfizer is seeking a Director, Integrated Insights & Strategy (IIS) to serve as the Obesity Lifecycle Forecasting Lead for Pfizer’s commercial obesity portfolio. This is a high-visibility, high-impact role responsible for building and owning the end-to-end forecast “truth” that informs leadership decisions across strategy, investment, resourcing, and performance management.
You will architect and run best-in-class patient-based forecast models that translate a complex and rapidly evolving obesity market into a defensible, decision-ready forecast. This includes stock-and-flow patient dynamics, regimen sequencing, initiation and discontinuation, persistence, switching, access dynamics, and the translation of patient flows into TRx/NBRx and demand. You will communicate forecast logic and assumptions with clarity and credibility from working teams through Pfizer senior executive leadership.
You will sit within the Global Commercial Analytics (GCA) organization and work in close partnership with brand marketing, finance, market research, and data science.
Role Responsibilities
Forecasting Architecture and Ownership:
Own and continuously evolve Pfizer’s obesity portfolio forecast architecture, including patient stock-and-flow models that explain and reconcile TRx/NBRx, demand, and revenue
Break down the market into transparent, modular components enabling clear explanation of each driver and assumption
Design model structures that handle real-world complexity: heterogeneous patient segments, prescriber channels, therapy lines, titration/maintenance patterns, adherence/persistence, and re-start behavior
Establish a clear linkage between epidemiology, market dynamics, product strategy, access/affordability, and observed utilization
Planning Cycles: LRF / Operating Plan / Performance Management
Lead development of Long-Range Forecasts (LRF) and Operating Plans, including scenario planning (base/upside/downside) and sensitivity of outcomes to key assumptions in clear executive narratives
Provide regular assessments of portfolio performance vs. forecast, identifying root causes, updating assumptions, and recommending actions
Produce decision-grade deliverables that support key governance moments (e.g., investment decisions, launch readiness, capacity planning, strategic prioritization)
Data & Evidence Integration
Integrate and reconcile diverse evidence streams including claims, EHR, payer/formulary/access data, demand/sales, primary market research, and analyst reports
Identify data gaps and propose new datasets, methods, and partnerships to improve capture of an evolving market
Partner with data science/engineering to improve scalability, traceability, and repeatability of the forecast process
Basic Qualifications
BA/BS in Engineering, Economics, Mathematics, or a related field required
8+ years in consulting, finance, or market analytics
5+ years at a high-value level (e.g., US & Global) developing data-driven brand strategy for key business assets
Demonstrated expertise designing complex pharma forecast models that connect patient dynamics to TRx and demand
Proven ability to influence and advise senior leadership; strong track record of executive-ready communication and storytelling
Strong proficiency in Excel-based modeling and PowerPoint communication with high standards for logic, structure, and clarity
Deep experience leveraging primary research and secondary data (e.g., claims, EHR, payer/access, sales/demand data) to develop defensible assumptions
Preferred Qualifications
MS, MBA, MPH, or PhD preferred
Experience in obesity/metabolic/cardiovascular categories; familiarity with access dynamics and real-world persistence patterns common to chronic therapies preferred
Proficiency with advanced analytics tools: Python/R, SQL, and visualization tools such as Tableau/Power BI preferred
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
Other Job Details
- Last Day to Apply: April 8, 2026
- Work Location Assignment: Hybrid, 2-3 days onsite/week, Commercial Pfizer site required
#PharmaForecasting #PatientBasedForecasting #ObesityMarketAnalytics
Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

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EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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Breakthroughs that change patients’ lives
Research confirms what intuition tells us: that purpose-driven companies perform better, are more innovative, attract and retain the best people, and know how to unleash the power of those people. Pfizer’s purpose—Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for building on our legacy as one of the greatest contributors of good to the world.
Each word in our purpose has meaning and reflects the value we strive to bring to patients and society:
“Breakthroughs” - These are the innovations, scientific and commercial, that we seek to deliver every day. All colleagues, regardless of role, level or location, strive for breakthroughs every day.
“Change” - We want to do more than simply improve patients’ medical conditions; we want to dramatically change their lives for the better.
“Patients’ lives” - We consider not only patients, but everyone they touch—including their families, caregivers, and friends—and everything they love to do. It’s an intentionally holistic view.
Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.
Every decision we make and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.
Our Values
To fully realize Pfizer’s purpose, we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.
The “how” is represented by four simple, powerful values—courage, excellence, equity, and joy—that define our company and our culture.
Courage: Breakthroughs start by challenging convention, especially in the face of uncertainty or adversity. This happens when we think big, speak up, and are decisive.
Excellence: We can only change patients’ lives when we perform at our best together. This happens when we focus on what matters, agree who does what, and measure our outcomes.
Equity: We believe that every person deserves to be seen, heard, and cared for. This happens when we are inclusive, act with integrity, and reduce healthcare disparities.
Joy: We give ourselves to our work, but it also gives to us. We find joy when we take pride, recognize one another, and have fun.
Benefits at Pfizer
Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues. Our Pay for Performance Philosophy and Practices reward colleagues based on the contributions they make to our business.
Our Competitive Benefits Programs help our colleagues by:
- Promoting Health and Wellness to help colleagues maintain and improve their physical and mental wellbeing. Pfizer offerings include health and disability insurance, preventative health programs, medical screenings, free or reduced-cost vaccinations, discounts on Pfizer products, mental health support, nutrition and fitness counseling and more.
- Strengthening Colleagues’ Financial Security by providing company contributions to retirement plans, life insurance and financial planning education to help colleagues achieve their financial goals.
- Providing Benefits and Time off for the Moments that Matter to ensure Pfizer colleagues have the time away from the office to recharge, recover and return to work as the best version of themselves. Vacation, Holiday time and Sick time are just the beginning, with a 12 week parental leave policy for both parents of a new born, 10 day of caregiver leave for those times when your family needs you whether it’s a child, spouse or parent, bereavement leave, and additional country-specific programs.
- And so much more, depending on your country and site, Pfizer offers childcare facilities or discount programs, on-site health and/or fitness centers, movement and mindfulness solutions, “Log in for your Day” work flexibility and so much more.
For U.S. based jobs, view an overview of Pfizer’s U.S. benefits program (opens in a new window)