Clinical Development Scientist, Director (Inflammation and Immunology)
- United States - Massachusetts - Cambridge
POSITION SUMMARY
You will provide medical and scientific leadership for one or more complex clinical trials within our Inflammation and Immunology portfolio. You will be responsible for the clinical integrity, scientific quality, and patient safety of clinical studies, partnering closely with Clinical Operations and cross‑functional stakeholders to deliver high‑quality, efficient trials that advance innovative medicines.
You will play a critical role in protocol development, study execution, data interpretation, and risk management, while serving as the primary clinical contact for investigators and internal study teams. This position offers the opportunity to influence both study‑level and program‑level clinical deliverables, contribute to regulatory filings, and support the development of clinicians through matrix leadership.
KEY RESPONSIBILITIES
Lead the clinical execution of one or more medium‑ to high‑complexity clinical studies with significant business impact
Provide clinical leadership in protocol design and development, ensuring operational feasibility, data quality, and participant/site engagement
Partner with Clinical Operations and cross‑functional teams to ensure timely, high‑quality study delivery
Oversee clinical data review, safety surveillance, and protocol deviation management, proactively identifying and mitigating clinical risks
Serve as the primary clinical contact for external investigators and internal stakeholders
Lead or support the establishment and oversight of Data Monitoring Committees (DMCs) and endpoint adjudication committees
Contribute clinical expertise to risk management, safety review, and integrated quality planning
Contribute and support key clinical documents, including informed consent documents, study reports, clinical development plans, Investigator brochures, scientific publications and clinical sections of regulatory submissions
Support regulatory interactions, audits, and inspections as needed
Drive continuous improvement and innovation in clinical development processes
Provide matrix leadership and mentoring to clinical colleagues as appropriate
MINIMUM QUALIFICATIONS
PhD/Pharm D in a relevant Science discipline and minimum of 5 years Clinical Research experience in the biopharmaceutical industry, OR
MS in a relevant Science discipline and minimum of 7 years of Clinical Research experience in the biopharmaceutical industry OR
BA/BS in a relevant Science discipline and minimum of 8 years Clinical Research experience in the biopharmaceutical industry
Deep knowledge of clinical development, ICH/GCP, global regulatory requirements, and safety management
Experience leading complex clinical studies and working effectively in cross‑functional, global teams
Strong written and verbal communication skills, with experience engaging internal and external stakeholders
PREFERRED QUALIFICATIONS
Advanced degree or professional certification in a scientific, medical, or healthcare related discipline,
Experience in respiratory and/or dermatology therapeutic areas
COMPETENCIES FOR SUCCESS
Demonstrates passion for helping patients
Flexibility to adapt and navigate through an ever-changing work environment while maintaining integrity and quality in the work assigned
Demonstrates autonomous delivery, problem-solving, and agile decision-making in execution of Clinical responsibilities
Promotes team health and exemplifies Pfizer’s leadership behaviors and actionable attitudes
Leverages knowledge and support from others related to overall objectives, strategy, critical issues, and policies
Demonstrates foresight and judgment to make complex decisions
Promotes innovation and takes appropriate risks to challenge the status quo in order to enhance the efficiency of current processes
Embraces evolving technologies and adopts best practices aimed at improving the efficiency and quality of clinical development
Has a global perspective and mindset. Works well in a diverse team environment with colleagues from diverse cultures, backgrounds, and geographies. both as a leader and a key contributor
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
WORK LOCATION ASSIGNMENT: This is a hybrid role requiring you to live within commuting distance and work on-site an average of 2.5 days per week.
PHYSICAL/MENTAL REQUIREMENTS
None
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
Potential for travel (including international)
Relocation support may be available
Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

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EEO & Employment Eligibility
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Breakthroughs that change patients’ lives
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Each word in our purpose has meaning and reflects the value we strive to bring to patients and society:
“Breakthroughs” - These are the innovations, scientific and commercial, that we seek to deliver every day. All colleagues, regardless of role, level or location, strive for breakthroughs every day.
“Change” - We want to do more than simply improve patients’ medical conditions; we want to dramatically change their lives for the better.
“Patients’ lives” - We consider not only patients, but everyone they touch—including their families, caregivers, and friends—and everything they love to do. It’s an intentionally holistic view.
Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.
Every decision we make and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.
Our Values
To fully realize Pfizer’s purpose, we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.
The “how” is represented by four simple, powerful values—courage, excellence, equity, and joy—that define our company and our culture.
Courage: Breakthroughs start by challenging convention, especially in the face of uncertainty or adversity. This happens when we think big, speak up, and are decisive.
Excellence: We can only change patients’ lives when we perform at our best together. This happens when we focus on what matters, agree who does what, and measure our outcomes.
Equity: We believe that every person deserves to be seen, heard, and cared for. This happens when we are inclusive, act with integrity, and reduce healthcare disparities.
Joy: We give ourselves to our work, but it also gives to us. We find joy when we take pride, recognize one another, and have fun.
Pfizer Research & Development
Pfizer Research & Development serves as the beating heart of Pfizer's trailblazing product pipeline, the essence of our mission to bring life-changing medicines to the world.
With an unwavering commitment to innovation, we use a multidisciplinary approach that blends scientific expertise, cutting-edge technologies, and strategic collaborations, igniting a powerful engine that propels groundbreaking discoveries into life-saving treatments for patients in need.
Through our relentless pursuit of progress, we envision a future where cutting-edge medicines pave the way to healthier, happier lives worldwide.
Benefits at Pfizer
Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues. Our Pay for Performance Philosophy and Practices reward colleagues based on the contributions they make to our business.
Our Competitive Benefits Programs help our colleagues by:
- Promoting Health and Wellness to help colleagues maintain and improve their physical and mental wellbeing. Pfizer offerings include health and disability insurance, preventative health programs, medical screenings, free or reduced-cost vaccinations, discounts on Pfizer products, mental health support, nutrition and fitness counseling and more.
- Strengthening Colleagues’ Financial Security by providing company contributions to retirement plans, life insurance and financial planning education to help colleagues achieve their financial goals.
- Providing Benefits and Time off for the Moments that Matter to ensure Pfizer colleagues have the time away from the office to recharge, recover and return to work as the best version of themselves. Vacation, Holiday time and Sick time are just the beginning, with a 12 week parental leave policy for both parents of a new born, 10 day of caregiver leave for those times when your family needs you whether it’s a child, spouse or parent, bereavement leave, and additional country-specific programs.
- And so much more, depending on your country and site, Pfizer offers childcare facilities or discount programs, on-site health and/or fitness centers, movement and mindfulness solutions, “Log in for your Day” work flexibility and so much more.
For U.S. based jobs, view an overview of Pfizer’s U.S. benefits program (opens in a new window)