Frontiers in Human Disease Symposium

14th Annual Pfizer Frontiers in Human Disease Symposium

The Role of Cilia in Biology and Medicine

May 4^th & 5^th 2022

The Pfizer Frontiers in Human Disease Symposium aims to address rapidly emerging areas of biomedical science and technology that will influence future development of novel therapeutics. This year’s topic,“The Role of Cilia in Biology and Medicine,” will be presented by widely recognized thought leaders who perform highly impactful research in the topic area.

Agenda

Wednesday, May 4th

9:15 a.m. – 9:30 a.m. ET

Log in

9:30 a.m. – 9:45 a.m. ET

Welcome – Morris J. Birnbaum, MD, PhD
Pfizer
Senior Vice President, Internal Medicine Research Unit

Opening Remarks – Peter Jackson, PhD
Stanford University School of Medicine
Professor of Microbiology and Immunology and of Pathology

Session 1

9:45 a.m. – 10:30 a.m. ET	Lukas Sommer, PhD University of Zurich Professor, Medical Faculty and Faculty of Science “ The Role of Cilia in Tumorigenesis” \| Abstract
10:30 a.m. – 11:15 a.m.	Jing Hughes, MD, PhD Washington University School of Medicine in St. Louis Associate Professor of Medicine, Division of Endocrinology, Metabolism & Lipid Research “Primary cilia in pancreatic islet function” \| Abstract
11:15 a.m. – 11:30 a.m. ET	Break
11:30 a.m. – 12:15 a.m. ET	Gaia Pigino, PhD Human Technopole Associate Head of Structural Biology Research Center “Structural cell biology of cilia and intraflagellar transport” \| Abstract
12:15 a.m. – 1:00 p.m. ET	Breakout Session: Group Networking/Office Hours with Session 1 speakers
1:00 p.m. – 2:00 p.m. ET	Lunch

Session 2

2:00 p.m. – 2:45 p.m. ET	Rajat Rohatgi, MD, PhD Stanford University School of Medicine Associate Professor of Biochemistry and of Medicine (Oncology) “ Cholesterol accessibility at the ciliary membrane regulates Hedgehog signaling” \| Abstract
2:45 p.m. – 3:30 p.m. ET	Ken-Ichi Takemaru, PhD Stony Brook University Professor, Department of Pharmacological Sciences “Chibby Family Members and Their Regulators in Ciliogenesis and Ciliopathies” \| Abstract
3:30 p.m. – 3:35 p.m. ET	Closing Remarks – Morris J. Birnbaum, M.D., Ph.D. Pfizer, SVP-Chief Scientific Officer, Internal Medicine Research Unit
3:35 p.m. - 4:20 p.m. ET	Breakout Session: Group Networking/Office Hours with Session 2 speakers
4:20 p.m. ET	End of Day 1

Thursday, May 5th

9:15 a.m. – 9:30 a.m.

Log in

9:30 a.m. – 9:45 a.m.

Welcome – Morris J. Birnbaum, MD, PhD
Pfizer
Senior Vice President, Internal Medicine Research Unit

Opening Remarks – Mikael Dolsten, MD, PhD
Pfizer
Chief Scientific Officer, President, Worldwide Research, Development and Medical

Session 3

9:45 a.m. – 10:30 a.m	Pleasantine Mill, PhD University of Edinburgh Group Leader, MRC Human Genetics Unit, Institute of Genetics and Cancer “Cilia in Development and Disease: Dynamics, Diversity and Reversing Disease Phenotypes” \| Abstract
10:30 a.m. – 11:15 a.m.	Bradley Yoder, PhD University of Alabama Professor / Chairperson, Cell, Developmental, and Integrative Biology “Cilia, injury, and cystic kidney diseases” \| Abstract
11:15 a.m. – 11:30 a.m.	Break
11:30 a.m. – 12:15 a.m.	Cecilia Lo, PhD University of Pittsburgh Distinguished Professor and F. Sargent Cheever Chair, Department of Developmental Biology “Cilia in the complex genetics of congenital heart disease” \| Abstract
12:15 a.m. – 1:00 a.m.	Breakout Session: Group Networking/Office Hours with Session 3 speakers
1:00 p.m. – 2:00 p.m.	Lunch

Session 4

2:00pm-2:45pm ET	David Clapham, MD, PhD Howard Hughes Medical Institute Janelia Group Leader “A serotonergic axon-cilium synapse drives nuclear signaling in the brain” \| Abstract
2:45pm-3:30pm ET	Peter Jackson, PhD Stanford University School of Medicine Professor of Microbiology and Immunology (Baxter Labs) and of Pathology “Ciliary Control of Metabolic Signaling” \| Abstract
3:30pm-3:35pm ET	Closing Remarks - Morris J. Birnbaum, MD, PhD Pfizer, SVP-Chief Scientific Officer, Internal Medicine Research Unit
3:35pm-4:20pm ET	Breakout Session: Group Networking/Office Hours with Session 4 speakers
4:20 ET	End of Symposium

14th Annual Pfizer Frontiers in Human Disease Symposium

The Role of Cilia in Biology and Medicine

May 4th & 5th 2022

Agenda

Hosts

Speakers

May 4^th & 5^th 2022