Groton, CT Site Statistics:

• Many of the discoveries and innovations that drive the Pfizer pipeline occur in the company’s world-class research and development laboratories in Groton, Connecticut.  Nearly every Pfizer medicine or vaccines has been developed, in part, in Groton, including Comirnaty, Paxlovid, Cibinqo, Litfulo and Abrysvo.
• The largest R&D facility in Pfizer, the campus was established in 1959, spans 160 acres, and contains 2.7M square feet of state-of-the-art laboratory facilities.
• Located in the Southeast corner of Connecticut, Groton is a coastal community on Long Island Sound.  It is equidistant to New York City and Boston and easily accessible to both cities via train.  Nearby airports in Hartford and Providence offer access to major metropolitan areas.

Functions

The following key R&D functions are located in Groton:

• Clinical Development & Operations
• Global Clinical Supply
• Comparative Medicine / Drug Safety Research & Development
• Medicine Design
• Pharmacokinetics, Dynamics & Metabolism
• Pharmaceutical Sciences 
• And many other business enablement functions.

Key Technologies

Many of Groton’s key scientific capabilities are not replicated anywhere else within Pfizer.  Our scientists are integral to translating laboratory breakthroughs into clinical trial realities.  The Flexible API Supply Technology (FAST) Lab, Solid Dose Manufacturing (SDM) line and Pfizer Continuous Manufacturing Module (PCMM) underpin the advancement of Pfizer’s clinical trials across all development phases.  Some additional key laboratory capabilities in Groton include:

• CryoEM: Our cryo-electron microscope allows our scientists to delve into the high-resolution structure of proteins with candidate medicines bound. This cutting-edge technology was instrumental in the development of the COVID-19 vaccine and is being utilized to revolutionize medical research.
• Pfizer Compound Library: Pfizer boasts an impressive arsenal of over 4 million chemical compounds, each meticulously preserved in our advanced cold liquid storage.  The Groton team ensures researchers worldwide have access to these invaluable samples, playing a pivotal role in global drug discovery.
• Vivarium: Our state-of-the-art vivarium facilities are the largest in the company, supporting studies that are crucial for drug development.  Pfizer’s animal care sets the industry standard while playing a vital role in ensuring safety for our patients.
• Anti-Counterfeit Lab: Since Pfizer established its anti-counterfeit lab in 2004, it has detected more than 302 million doses of counterfeit medicines, helping to ensure that our lifesaving medicines reach the patients who need them safely and securely.