Pfizer Inc. announced today that Kathrin U. Jansen, Ph.D., has been appointed Senior Vice President, Vaccine Research & Development, and will be responsible for leading all Pfizer vaccine research and development programs, effective June 1st, 2015. Dr. Jansen will report directly to Mikael Dolsten, M.D., Ph.D., President of Worldwide Research and Development at Pfizer, and will be based in Pfizer’s Pearl River, New York research site.

“With over two decades of experience as a vaccine researcher, Kathrin is a world-class scientist with a remarkable track-record of delivering first-in-class vaccines in areas with serious unmet patient need such as human papillomavirus infection and Neisseria meningitidis serogroup B,” said Dr. Dolsten. “She has also played a pivotal role in advancing Pfizer’s Staphylococcus aureus and Clostridium difficile vaccine candidate programs, the licensure of Prevnar 13 in both infant and adult indications, and the development of the diagnostic assays that enabled the CAPiTAi. I am confident that she will continue to lead our Vaccine Research organization with a sharp focus on delivering potential vaccine breakthroughs for infectious diseases.”

Dr. Jansen was previously Chief Scientific Officer of Pfizer’s Vaccine Research and Early Development Research Unit. Dr. Jansen’s Pfizer career started when she joined Wyeth, now a wholly owned subsidiary of Pfizer, in 2006, where she was responsible for leading vaccine research with a focus on infectious disease targets, early development and clinical testing. Earlier in her career, Dr. Jansen served as VaxGen's Chief Scientific Officer and Senior Vice President for Research and Development and also directed a number of vaccine research efforts at Merck Research Laboratories, including the company’s novel bacterial vaccine programs. Her efforts led to the licensure of the world's first cervical cancer vaccine for the prevention of human papillomavirus infection (HPV).

“There is a remarkable scientific opportunity in vaccine research ahead of us and Pfizer’s vaccine research and development team is fully focused on addressing major neonatal, infant, adolescent and adult infections and pioneering therapeutic immunotherapy across diseases including cancer,” said Dr. Jansen. “We are building on the rich foundation of our scientific heritage with Prevnar and other vaccines to design and develop vaccine candidates that are unique - and most importantly - with the potential to significantly improve patients’ lives.”

Dr. Jansen received her doctoral degree in microbiology, biochemistry and genetics from Phillips Universität, Marburg, Germany. Following completion of her formal training and postdoctoral work at the Institute for Mikrobiologie in Marburg, Dr. Jansen continued her postdoctoral training with Professor G.P. Hess at Cornell University. She then joined the Glaxo Institute for Molecular Biology in Geneva, Switzerland. Since 2010, Dr. Jansen has been adjunct professor at the University of Pennsylvania School Of Medicine.

Dr. Jansen will succeed Dr. Emilio Emini, who has accepted a position at the Bill & Melinda Gates Foundation as the head of their HIV program.

Dr. Jansen will lead an organization of approximately 550 colleagues comprised of clinicians, vaccine process/analytical/and formulation development, and other laboratory scientists. Vaccine Research and Development Unit includes Vaccine Research and Early Development, Vaccine Immunotherapeutics, Vaccine Clinical Research and Vaccine Operations and High Throughput Clinical Testing. As of February 2015, Pfizer’s clinical vaccine pipeline includes five programs from Phase I through III targeting diseases caused by Staph aureus, Clostridium difficile and Meningitis B, as well as smoking cessation and asthma.

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At Pfizer, we apply science and our global resources to bring therapies to people that extend and significantly improve their lives. We strive to set the standard for quality, safety and value in the discovery, development and manufacture of health care products. Our global portfolio includes medicines and vaccines as well as many of the world's best-known consumer health care products. Every day, Pfizer colleagues work across developed and emerging markets to advance wellness, prevention, treatments and cures that challenge the most feared diseases of our time. Consistent with our responsibility as one of the world's premier innovative biopharmaceutical companies, we collaborate with health care providers, governments and local communities to support and expand access to reliable, affordable health care around the world. For more than 150 years, Pfizer has worked to make a difference for all who rely on us. To learn more, please visit us at www.pfizer.com.

DISCLOSURE NOTICE: The information contained in this release is as of April 6, 2015. Pfizer assumes no obligation to update forward-looking statements contained in this release as the result of new information or future events or developments.

This release contains forward-looking information about Pfizer’s research and development and pipeline of vaccines that involve substantial risks and uncertainties that could cause actual results to differ materially from those expressed or implied by such statements. Risks and uncertainties include, among other things, the uncertainties inherent in research and development, including, without limitation, the ability to meet anticipated clinical trial commencement and completion dates as well as the possibility of unfavorable clinical trial results, including unfavorable new clinical data and additional analyses of existing clinical data; whether and when regulatory submissions may be made in any jurisdictions for any of these pipeline products; whether and when such applications may be approved by regulatory authorities, which will depend on the assessment by such regulatory authorities of the benefit-risk profile suggested by the totality of the efficacy and safety information submitted; decisions by regulatory authorities regarding labeling and other matters that could affect the availability or commercial potential of any of these pipeline products; and competitive developments.

A further description of risks and uncertainties can be found in Pfizer's Annual Report on Form 10-K for the fiscal year ended December 31, 2014 and in its subsequent reports on Form 10-Q, including in the sections thereof captioned "Risk Factors" and "Forward-Looking Information That May Affect Future Results", as well as in its subsequent reports on Form 8-K, all of which are filed with the SEC and available at www.sec.gov and www.pfizer.com.

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i Community-Acquired Pneumonia Immunization Trial In Adults (CAPiTA)