Pipeline Discoveries for Autoimmune Diseases and Chronic Inflammation
Inflammation Immunology Drug Pipeline & Clinical Trials
Pfizer's mission is to deliver medicines that make a real difference in quality of life for patients with autoimmune diseases and chronic inflammation. Scientists in our research and development (R&D) programs are committed to speeding the delivery of new treatments. We pledge to maintain the safety of patients who take part in our trials and to uphold the highest ethical standards in all of our research initiatives.
On this page, you will find more information about our pipeline, which investigational therapies are under development, and in which stages.
If you are a Health Care Professional and interested in further details (including pathways being explored, mechanisms of action of investigational compounds, and an overall summary of investigational compounds organized by therapy area and disease state), please visit our in-depth Pfizer Immunology & Inflammation Research Pipeline site.
- 00 Phase 1
- 00 Phase 2
- 00 Phase 3
- 00 Registration
- 00 Total
PF-07868489 | New project
Pulmonary Arterial Hypertension (Biologic) (ORPHAN - U.S.)
anti-BMP9
PF-07899895 | New project
Ulcerative Colitis
SIK inhibitor
PF-07261271 | New project
Inflammatory Bowel Disease (Biologic)
p40/TL1a bi-specific
PF-07054894 | New project
Inflammatory Bowel Disease
CCR6 antagonist
PF-06835375 | New project
Lupus (Biologic)
anti-CXCR5
VELSIPITY (etrasimod) | New project
Alopecia Areata
S1P inhibitor
VELSIPITY (etrasimod) | New project
Atopic Dermatitis
S1P inhibitor
dazukibart (PF-06823859) | New project
Lupus (Biologic)
IgG1 neutralizing monoclonal antibody against IFN-b
PF-07264660 | New project
Atopic Dermatitis (Biologic)
anti-IL-4/ IL-13/ IL-33
PF-07275315 | New project
Atopic Dermatitis (Biologic)
anti-IL-4/ IL-13/ TSLP
PF-06835375 | New project
Immune Thrombocytopenic Purpura (Biologic)
anti-CXCR5
VELSIPITY (etrasimod) | New project
Eosinophilic Esophagitis
S1P inhibitor
VELSIPITY (etrasimod) | New project
Crohn's disease
S1P inhibitor
Dekavil | New project
Rheumatoid Arthritis (Biologic)
IL-10
LITFULO (ritlecitinib) | New project
Crohn's Disease
JAK3/TECinhibitor
LITFULO (ritlecitinib) | New project
Ulcerative Colitis
JAK3/TECinhibitor
fordadistrogene movaparvovec (PF-06939926) | New project
Duchenne Muscular Dystrophy Ambulatory (Biologic) (2-3 year-old boys)
Gene therapy, minidystrophin
fordadistrogene movaparvovec (PF-06939926) | New project
Duchenne Muscular Dystrophy Ambulatory (Biologic) (FAST TRACK, RPD - U.S.; ORPHAN - U.S., E.U.)
Gene therapy, minidystrophin
dazukibart (PF-06823859) | New project
Dermatomyositis, Polymyositis (Biologic) (ORPHAN - U.S. E.U., FAST TRACK - U.S., PRIME - E.U.)
IgG1 neutralizing monoclonal antibody against IFN-b
LITFULO (ritlecitinib) | New project
Vitiligo
JAK3/TEC inhibitor