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Sandwich, UK

Functions: Pharmatherapeutics Pharmaceutical Sciences, Worldwide Safety and Regulatory

Business Units: Primary Care

Key Technologies: Active Pharmaceutical Ingredient (API) Route Design, Development and Manufacturing; Analytical Science Drug Product Design and Development; Drug Product Manufacture; Regulatory Chemistry Manufacturing and Control (CMC) Strategy; Good Manufacturing Process (GMP) Quality Assurance; Materials Science

Pfizer sold the research part at Sandwich, named Discovery Park, in July 2012 to Discovery Park Limited and the site is now multi-tenanted. Pfizer has retained a strong presence in the local area since establishing operations in Sandwich in 1954, and is now part of the Discovery Park site. A number of Pfizer capabilities critical to the delivery of the company's mid to late stage portfolio are located at Discovery Park. These include Pharmaceutical Sciences; Medical Regulatory; Business Units; Quality Assurance; and Business Support Functions (Procurement & Operation, HR, Finance, Patents).

As part of the Pharmaceutical Sciences operation, Pfizer's unique pilot plant production plays an essential role within Pfizer’s drug development process, supplying Active Pharmaceutical Ingredient (API) to small molecule clinical trial programs. A highly flexible, multipurpose facility, it carries out a wide range of chemical synthesis to support programs from early molecule development through to preparation for commercial market launch. Pharmaceutical Sciences, operations at Sandwich also include key functions that support clinical trials, including GMP facilities for manufacturing solid and sterile/liquid drug product dosage forms, clinical packaging and labeling, and inventory management. Additionally, the Global Operations (GO), Quality Assurance (QA), GMP Analytics, and Global Clinical Supply (GCS) groups are located here, providing fully integrated capabilities for delivering clinical supply materials to the global Pfizer organization. 

Historically the Sandwich site has an excellent track record of discovering new medicines to improve the health and quality of life of people suffering from critical diseases. Some of Pfizer's most important medicines were discovered at Sandwich. They include Celsentri® (maraviroc); Revatio® (sildenafil); Diflucan (fluconazole) and Vfend® (voriconazole); Istin (amlodipine) and Cardura (doxazosin); and Viagra® (sildenafil).