Sr. Director, Cloud and Infrastructure Transformation
- United States - New York - New York City
ROLE SUMMARY
At the heart of Pfizer's Digital transformation sits Infrastructure & Cloud, enabling modern cloud infrastructure and engineering capabilities that influence business outcomes and provide value to our business, shareholders, and patients every day.
Pfizer is seeking an execution-focused Senior Director to lead transformational cloud and infrastructure initiatives that directly enable breakthrough science and drug discovery. You'll play a critical leadership role in developing our next-generation cloud platform for AI/ML-powered research while building and leading a high-performing technical team.
This role combines strategic thinking with hands-on delivery, technical depth with leadership impact, and the autonomy to make decisions that advance Pfizer's mission. Your work will provide the infrastructure foundation that enables our scientists to accelerate research, analyze complex data, and develop treatments that improve patients' lives.
Pfizer seeks individuals that are highly self-motivated, eager to learn, and effective when working in a team environment. A strong aptitude towards self-development, continuous learning, and growth is highly desired.
ROLE RESPONSIBILITIES
The Senior Director, Cloud and Infrastructure Transformation provides executive-level technical leadership and strategic direction, playing a critical role in ensuring Pfizer continues to leverage cloud-native design patterns and modern infrastructure practices at enterprise scale. This role will help ensure our Infrastructure & Cloud organization delivers secure, compliant, productive, and innovative platforms that enable breakthrough science.
You will lead a team of 3-5 Directors and Senior Managers and Directors, providing strategic guidance, mentorship, and support in their professional development while driving the adoption of transformational cloud and infrastructure initiatives across the organization.
Lead enterprise cloud and infrastructure transformation, including AI/ML platforms, data center migration, and network transformation
Drive multi‑cloud, data center, and network initiatives with strong execution
Make high‑impact architectural and technology decisions
Provide senior technical leadership and shape infrastructure strategy
Lead and develop senior leaders and high‑performing teams
Partner with security, digital, and business stakeholders
Operate effectively in a global, matrixed organization
BASIC QUALIFICATIONS
Bachelor’s degree in information technology, Computer Science, Computer Engineering, or a similar discipline
12+ years in infrastructure, cloud, and networking with proven track record of delivering complex, multi-year transformation programs
Deep multi-cloud expertise (AWS, Azure, GCP) with hands-on experience building production platforms at scale
Comprehensive understanding of the full stack from on-premises data centers to cloud-native architectures
Demonstrated success managing and developing senior technical leaders (Senior Managers, Directors)
Extensive experience leading through influence in matrixed organizations, working across technical and business stakeholders
Strong technical judgment shaped by real-world experience delivering at scale - hands-on when needed, strategic enough to delegate and orchestrate
Expertise in modern cloud-native architectures, IaC (Terraform/OpenTofu), DevOps practices, automation, and security/compliance in regulated industries
Excellent communicator with the ability to translate technical complexity for diverse audiences and drive alignment
Proven ability to deliver results while managing multiple complex initiatives simultaneously
Pragmatic decision-maker who balances ideal solutions with practical constraints and knows when to seek input or escalate
PREFERRED QUALIFICATIONS
AI/ML infrastructure experience, especially supporting research and data science workloads
Background in pharma, biotech, or highly regulated industries
Cloud certifications demonstrating depth of expertise
Experience with large-scale migrations, datacenter exits, or M&A integrations
Global team management across time zones and cultures
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
10-20% Travel
Work Location Assignment: Hybrid
Last Date to Apply for Job: 3/12/2026
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Pfizer endeavors to make www.pfizer.com/careers accessible to all users. If you would like to contact us regarding the accessibility of our website or need assistance completing the application process and/or interviewing, please email disabilityrecruitment@pfizer.com. This is to be used solely for accommodation requests with respect to the accessibility of our website, online application process and/or interviewing. Requests for any other reason will not be returned.
Breakthroughs that change patients’ lives
Research confirms what intuition tells us: that purpose-driven companies perform better, are more innovative, attract and retain the best people, and know how to unleash the power of those people. Pfizer’s purpose—Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for building on our legacy as one of the greatest contributors of good to the world.
Each word in our purpose has meaning and reflects the value we strive to bring to patients and society:
“Breakthroughs” - These are the innovations, scientific and commercial, that we seek to deliver every day. All colleagues, regardless of role, level or location, strive for breakthroughs every day.
“Change” - We want to do more than simply improve patients’ medical conditions; we want to dramatically change their lives for the better.
“Patients’ lives” - We consider not only patients, but everyone they touch—including their families, caregivers, and friends—and everything they love to do. It’s an intentionally holistic view.
Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.
Every decision we make and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.
Our Values
To fully realize Pfizer’s purpose, we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.
The “how” is represented by four simple, powerful values—courage, excellence, equity, and joy—that define our company and our culture.
Courage: Breakthroughs start by challenging convention, especially in the face of uncertainty or adversity. This happens when we think big, speak up, and are decisive.
Excellence: We can only change patients’ lives when we perform at our best together. This happens when we focus on what matters, agree who does what, and measure our outcomes.
Equity: We believe that every person deserves to be seen, heard, and cared for. This happens when we are inclusive, act with integrity, and reduce healthcare disparities.
Joy: We give ourselves to our work, but it also gives to us. We find joy when we take pride, recognize one another, and have fun.
Pfizer Digital
Pfizer Digital takes immense pride in being at the forefront of innovation, harnessing cutting-edge smart technology that profoundly impacts the lives of our patients.
With the transformative potential of digital solutions, we revolutionize how we discover, develop, and deliver medicines, enabling us to achieve breakthroughs faster and more efficiently.
By streamlining and automating transactional processes, we create valuable time and resources, empowering our talented team to focus on meaningful work that truly makes a difference in healthcare and beyond.
Benefits at Pfizer
Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues. Our Pay for Performance Philosophy and Practices reward colleagues based on the contributions they make to our business.
Our Competitive Benefits Programs help our colleagues by:
- Promoting Health and Wellness to help colleagues maintain and improve their physical and mental wellbeing. Pfizer offerings include health and disability insurance, preventative health programs, medical screenings, free or reduced-cost vaccinations, discounts on Pfizer products, mental health support, nutrition and fitness counseling and more.
- Strengthening Colleagues’ Financial Security by providing company contributions to retirement plans, life insurance and financial planning education to help colleagues achieve their financial goals.
- Providing Benefits and Time off for the Moments that Matter to ensure Pfizer colleagues have the time away from the office to recharge, recover and return to work as the best version of themselves. Vacation, Holiday time and Sick time are just the beginning, with a 12 week parental leave policy for both parents of a new born, 10 day of caregiver leave for those times when your family needs you whether it’s a child, spouse or parent, bereavement leave, and additional country-specific programs.
- And so much more, depending on your country and site, Pfizer offers childcare facilities or discount programs, on-site health and/or fitness centers, movement and mindfulness solutions, “Log in for your Day” work flexibility and so much more.
For U.S. based jobs, view an overview of Pfizer’s U.S. benefits program (opens in a new window)