Medical Affairs AI Operations Lead
- United States - Illinois - Lake Forest
- United States - California - La Jolla
- United States - Massachusetts - Cambridge
- United States - Washington – Bothell
- United States - Pennsylvania - Collegeville
- United States - New York - New York City
ROLE SUMMARY
The Medical Affairs AI Operations Lead is the execution engine for AI transformation and responsible for assessing and redesigning Medical Affairs workflows, building AI playbooks for AI-assisted work, driving enablement, and sustained adoption across HQ Medical Affairs and Field Medical. This role ensures AI capabilities translate into measurable productivity improvements and durable behavior change by embedding AI into existing habits, deploying role-based training, establishing feedback loops, and coordinating rollouts across regions and functions.
ROLE RESPONSIBILITIES
Conduct systematic workflow assessments across HQ Medical Affairs and Field Medical to identify high-impact AI transformation opportunities.
Document current-state processes (inputs, steps, outputs, templates) to create structured specifications for AI-enabled workflow design.
Prioritize workflow opportunities using impact–effort analysis and operational readiness, in partnership with the Medical Affairs AI Lead.
Design AI-enabled operating models: workflow playbooks with decision trees, quality checkpoints, and escalation protocols.
Create standardized operating procedures (SOPs) for AI-abssisted processes that meet compliance and regulatory requirements.
Partner with Compliance to ensure workflows support MLR review requirements, adverse event reporting obligations, and promotional/non-promotional guidelines.
Design and deliver role-based AI literacy and enablement programs (e.g., Field Medical, Medical Directors, Medical Information, Publications).
Implement habit-stacking and coaching strategies to integrate AI naturally into existing workflows and daily routines.
Identify and develop AI champions within functions to provide peer support and accelerate grassroots adoption.
Create and communicate success stories and case studies that demonstrate impact in relatable, function-specific terms.
Build feedback collection mechanisms and continuous improvement loops to enhance AI output quality (accuracy and usability).
Coordinate with regional Medical Affairs teams to adapt playbooks to local requirements and support global rollout.
BASIC QUALIFICATIONS
Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.
Advanced degree in life sciences, pharmacy, or related field (PharmD, PhD, MD, or equivalent preferred).
5+ years of experience in Medical Affairs (HQ or Field) with hands-on experience.
Strong fluency with generative AI tools; hands-on familiarity with LLM APIs and context engineering.
Proven experience in process improvement, workflow optimization, and/or operational excellence initiatives.
Strong project management skills with the ability to manage multiple initiatives simultaneously.
Experience navigating compliance and regulatory requirements in the pharmaceutical industry and working effectively within enterprise governance.
PREFERRED QUALIFICATIONS
Experience leading digital transformation or technology adoption initiatives.
Familiarity with AI/ML concepts, agentic workflows, and automation tools.
Experience with Medical Affairs systems (e.g., Veeva, Salesforce) and collaborating on secure integrations with Technology teams.
Exposure to testing and monitoring approaches for AI systems (prompt testing, output validation, regression testing, drift monitoring).
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
Work Location Assignment: Hybrid. Must be able to work in assigned Pfizer office 2-3 days per week, or as needed by the business
Other Job Details
Last Date to Apply for Job: April 30, 2026
This posting covers multiple available positions.
Eligible for Relocation Package: No
Relocation assistance may be available based on business needs and/or eligibility.

Candidates must be authorized to be employed in the U.S. by any employer.
U.S. work visa sponsorship (such as TN, O-1, H-1B, etc.) is not available for this role now or in the future.

Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider’s name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
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Breakthroughs that change patients’ lives
Research confirms what intuition tells us: that purpose-driven companies perform better, are more innovative, attract and retain the best people, and know how to unleash the power of those people. Pfizer’s purpose—Breakthroughs that change patients' lives—fuels everything we do and reflects our passion for building on our legacy as one of the greatest contributors of good to the world.
Each word in our purpose has meaning and reflects the value we strive to bring to patients and society:
“Breakthroughs” - These are the innovations, scientific and commercial, that we seek to deliver every day. All colleagues, regardless of role, level or location, strive for breakthroughs every day.
“Change” - We want to do more than simply improve patients’ medical conditions; we want to dramatically change their lives for the better.
“Patients’ lives” - We consider not only patients, but everyone they touch—including their families, caregivers, and friends—and everything they love to do. It’s an intentionally holistic view.
Our purpose ensures that patients remain at the center of all we do. We live our purpose by sourcing the best science in the world; partnering with others in the healthcare system to improve access to our medicines; using digital technologies to enhance our drug discovery and development, as well as patient outcomes; and leading the conversation to advocate for pro-innovation/pro-patient policies.
Every decision we make and every action we take is done with the patient in mind—and to nurture an environment where breakthroughs can thrive.
Our Values
To fully realize Pfizer’s purpose, we have established a clear set of expectations regarding “what” we need to achieve for patients and “how” we will go about achieving those goals.
The “how” is represented by four simple, powerful values—courage, excellence, equity, and joy—that define our company and our culture.
Courage: Breakthroughs start by challenging convention, especially in the face of uncertainty or adversity. This happens when we think big, speak up, and are decisive.
Excellence: We can only change patients’ lives when we perform at our best together. This happens when we focus on what matters, agree who does what, and measure our outcomes.
Equity: We believe that every person deserves to be seen, heard, and cared for. This happens when we are inclusive, act with integrity, and reduce healthcare disparities.
Joy: We give ourselves to our work, but it also gives to us. We find joy when we take pride, recognize one another, and have fun.
Benefits at Pfizer
Pfizer offers competitive compensation and benefits programs designed to meet the diverse needs of our colleagues. Our Pay for Performance Philosophy and Practices reward colleagues based on the contributions they make to our business.
Our Competitive Benefits Programs help our colleagues by:
- Promoting Health and Wellness to help colleagues maintain and improve their physical and mental wellbeing. Pfizer offerings include health and disability insurance, preventative health programs, medical screenings, free or reduced-cost vaccinations, discounts on Pfizer products, mental health support, nutrition and fitness counseling and more.
- Strengthening Colleagues’ Financial Security by providing company contributions to retirement plans, life insurance and financial planning education to help colleagues achieve their financial goals.
- Providing Benefits and Time off for the Moments that Matter to ensure Pfizer colleagues have the time away from the office to recharge, recover and return to work as the best version of themselves. Vacation, Holiday time and Sick time are just the beginning, with a 12 week parental leave policy for both parents of a new born, 10 day of caregiver leave for those times when your family needs you whether it’s a child, spouse or parent, bereavement leave, and additional country-specific programs.
- And so much more, depending on your country and site, Pfizer offers childcare facilities or discount programs, on-site health and/or fitness centers, movement and mindfulness solutions, “Log in for your Day” work flexibility and so much more.
For U.S. based jobs, view an overview of Pfizer’s U.S. benefits program (opens in a new window)