How Drugs Are Made

The medicines available today have taken an average of 12 years to develop. With dedication, creativity, and science, we can significantly cut that time.
Pipeline Snapshot as of November 4, 2025


As a 175-year-old American company, we’re proud to lead the world in medical innovation. Our U.S. supply, manufacturing, and distribution sites are focused on ensuring that all Pfizer products are made to the highest standards of quality, safety, and efficacy.
Pfizer operates 11 manufacturing sites and two distribution centers located in nine states across the U.S.
The 70-acre site in Andover combines state-of-the-art research and development facilities with flexible, multi-product manufacturing capabilities.
In Franklin, our 48,000-square-foot facility manufactures heparin active pharmaceutical ingredient (API).
The 1,300 acre facility located in Kalamazoo, Michigan manufactures active pharmaceutical ingredients (API) and drug product (DP).
The McPherson site specializes in manufacturing sterile injectable medicines used daily in hospitals around the world.
Since 1982, the Middleton site has focused on the manufacture of biologics. The 83,000-square-foot facility isolates bovine thrombin, a naturally occurring enzyme which plays a critical role in rapid clotting (hemostasis) of blood.
The North Creek site, integrated into Pfizer’s network following the Seagen acquisition, produces antibody drug conjugates (ADCs) and antibody intermediates.
With more than 100 years of rich history in innovation and manufacturing excellence, 19 products- including various vaccines, antibiotics, and oncology medicines, have been discovered, developed, and approved at the Pearl River, New York site.
In Rochester, Michigan, the site manufactures and packages penicillin, the only approved treatment for late stage syphilis.
The Rocky Mount, North Carolina site has 1.4 million square feet of manufacturing space on 250 acres in Eastern North Carolina.
The 230-acre site in Sanford, North Carolina site has flexible, multi-product manufacturing capabilities and facilities.
Once operational, the Sanford North facility will have the capabilities for producing biologics.


