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Read our latest stories on the people and scientific innovations making a difference in patients’ lives.
Science & Innovation
Zinc Finger Transcription Factors: The On/Off Switch for Genes Inspired by Frogs
Have you ever noticed how effortlessly frogs cling to nearly every surface? Their sticky little fingers easily grab and hold onto just about anything they want. It turns out that the frogs have protein structures that do the same thing, and these structures could be the key to unlocking therapies for amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD), two of the most debilitating neurological conditions affecting millions of people today. While studying the African clawed...
Science & Innovation
Why Are Some People Tastier to Mosquitoes Than Others?
Do mosquitos prefer a certain blood type? Maybe—but it’s not just one factor that influences why these winged pests are attracted to us and researchers can’t seem to agree on a definitive answer.1,2There are two kinds of people in the world: those who return from time in the outdoors covered in itchy mosquito bites and those who can spend hours in the same space and avoid getting bitten at all. Let's face it, mosquitoes are not equal opportunity feasters.So, what exactly makes some people more...
Science & Innovation
Maternal Immunization: Protecting Children from RSV and GBS
In the first few months of their lives, infants experience new sights, sounds, scents, and textures. During this time, they also make contact with new organisms. It takes up to three months for portions of infants’ still-developing immune systems to mature.1 During these early weeks and months, infants are too young to receive their first vaccines, leaving them vulnerable to developing serious infections.2Most pregnant people transmit antibodies to their developing fetuses naturally starting in...
Science & Innovation
Diabetes Breakthroughs Focus on Making Daily Life Easier
New research and emerging innovations are constantly evolving when it comes to helping patients manage, and maybe even prevent, Type 2 diabetes. The days of tender fingertips and painful injections may not be over, but alternatives are becoming more and more commonplace. Diabetes affects over 37 million people in the United States, slightly more than 11% of the population.1 Type 2 diabetes accounts for more than 95% of all diabetes.2 Game-changing breakthroughs, such as continuous glucose...
Science & Innovation
How to Manage High Blood Pressure (With the Help of a Few Giraffes)
People have long adored giraffes for their friendly faces, their tall and somewhat strange stature and, of course, those impossibly long necks. Now, researchers believe that giraffes may also offer physiological insights into certain health conditions. With a neck that can be longer than six feet, giraffes seemingly should struggle with the consequences of high blood pressure, also known as hypertension, because of their blood's substantial uphill climb from the heart to the brain. But they...
Living & Wellbeing
6 Mosquito Diseases That Can Be Deadly
Mosquitoes won’t just ruin a cookout or leave angry red welts on your skin after a blood meal; the little buzzers might also transmit serious diseases. Mosquitoes are "silent" feeders; their siphon-like mouthparts can quickly pierce human skin and feed on blood without causing any notice, says Patrick Kelly PhD, director of Global Epidemiology for Tick Borne Diseases for Pfizer. He calls it “highly efficient feeding that has been fine-tuned over millions of years.” Mosquitos have taken...
Purpose & Ideals
Why Medicine Flavor Matters in Drug Design, Especially for Kids
Medicines don’t work unless people take them. It sounds like an obvious statement. And yet, a large percentage of people—up to 50%1 even—struggle when it comes to swallowing medications. Medicine flavoring has been a big part of the problem. For more than a decade, Jeremy Bartlett, Ph.D., a Research Fellow with Pfizer Drug Product Design in Groton, Connecticut, has been working to solve that problem. “We work in pharmaceutical sciences, and if we develop a medicine you’re supposed to take and...
Living & Wellbeing
5 Things Worth Knowing About Biosimilars and Interchangeability
Biologic drugs have revolutionized disease management for many serious and chronic conditions including cancer, rheumatoid arthritis, Crohn’s disease, and psoriasis.1 Versions of biologic drugs, known as biosimilars, have helped improve access to these critical medicines for a wider patient population and lowered healthcare costs.2As biosimilars continue to hit the market in greater numbers, you’ll be hearing more about this class of drugs, as well as the “interchangeability” designation that...
Real People
Bill Sessa is Ready to Deliver Breakthroughs for Common Diseases
“Despite advances in treatment, cardiovascular disease is still the number one killer worldwide,” says Bill Sessa, who joined Pfizer as Senior Vice President and Chief Scientific Officer for the Internal Medicine Research Unit (IMRU) in February 2022. “For decades, Pfizer has been at the forefront of advancing novel treatments for people living with cardiovascular and other conditions that affect a significant portion of the world’s population," Sessa says. "I’m thrilled to have the chance to...
Purpose & Ideals
Pfizer’s Institute of Translational Equitable Medicine Addresses Equity in Health Research
When it comes to healthcare, the terms “equitable” and "access" often go hand-in-hand. In order to prevent, treat, and identify diseases that disproportionately impact underserved and minority populations, Pfizer believes that research must be directed to the root causes of healthcare disparities. The recently-launched Institute of Translational Equitable Medicine (ITEM) is intended to do just that: work toward a more equitable future of health care. For Aida Habtezion, M.D., who is Pfizer’s...
Living & Wellbeing
How Wearable Technology is Helping Scientists Better Understand Patients and Diseases
Like many people, Tim McCarthy, PhD, wears a watch that tracks his steps and monitors his activity levels. That watch also represents something else for McCarthy, who is Pfizer’s Head of Digital Medicine & Translational Imaging, which is part of Early Clinical Development in the company’s Worldwide Research, Development, and Medical Organization. For him, wearable technology could hold the power to better understand patients and diseases to improve healthcare. McCarthy acknowledges it’s still...
Trusted Voices
Thanking Rod MacKenzie for his countless contributions to Pfizer
Thanking Rod MacKenzie for his countless contributions to Pfizer, the industry and patients around the globe. After 35 years of outstanding service to Pfizer, Rod MacKenzie, PhD, Chief Development Officer and Executive Vice President, has informed me of his intent to retire early next year. This is a bittersweet time for me and for all those colleagues who have worked with Rod over the course of his career. I will miss working with my friend, but I am excited to see the wonderful things he...
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